{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T06:29:36Z","timestamp":1783405776797,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Interventional Cardiology"],"published-print":{"date-parts":[[2019,10,24]]},"abstract":"<jats:p><jats:italic>Background\/Aim<\/jats:italic>. The RISK-PCI is a simple score for the prediction of 30-day major adverse cardiovascular events (MACE) and mortality in patients treated with primary PCI (pPCI). The aim of the present study is to evaluate the prognostic performance of the RISK-PCI score in predicting MACE and mortality in the long-term follow-up of STEMI patients treated with pPCI. <jats:italic>Method<\/jats:italic>. The present study enrolled 2,096 STEMI patients treated with pPCI included in the RISK-PCI trial. Patients presenting with cardiogenic shock were excluded. The composite end-point MACE comprising cardiovascular mortality, nonfatal reinfarction and stroke. Patients were followed up at 6 years after enrollment. <jats:italic>Results<\/jats:italic>. One-year and 6-year MACE occurred in 229 (10.9%) and 285 (13.6%) patients, respectively; and 1-year and 6-year mortality occurred in 128 (6.2%) and 151 (7.2%) patients, respectively. The RISK-PCI score was an independent predictor for 1-year MACE (HR 1.24, 95% CI 1, 18\u20131.31, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>), 6-year MACE (HR 1.22, 95% CI 1.16\u20131.28, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>), 1-year mortality (HR 1.21, 95% CI 1.13\u20131.29, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>), and 6-year mortality (HR 1.23, 95% CI 1.15\u20131.31, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>). The discrimination of the RISK-PCI score to predict 1-year and 6-year MACE and mortality was good: for 1-year MACE c-statistic 0.78, for 6-year MACE c-statistic 0.75, for 1-year mortality c-statistic 0.87, and for 6-year mortality c-statistic 0.83. The nonsignificant Hosmer\u2013Lemeshow goodness-of-fit estimates for 1-year MACE (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.619<\/mml:mn><\/mml:mrow><\/mml:math>), 6-year MACE (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.319<\/mml:mn><\/mml:mrow><\/mml:math>), 1-year mortality (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.258<\/mml:mn><\/mml:mrow><\/mml:math>), and 6-year mortality (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.540<\/mml:mn><\/mml:mrow><\/mml:math>) indicated a good calibration of the model. <jats:italic>Conclusion<\/jats:italic>. The RISK-PCI score demonstrates good characteristics in the assessment of the risk for the occurrence of MACE and mortality during long-term follow-up after pPCI.<\/jats:p>","DOI":"10.1155\/2019\/2679791","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T19:30:55Z","timestamp":1571945455000},"page":"1-9","source":"Crossref","is-referenced-by-count":11,"title":["Using the RISK-PCI Score in the Long-Term Prediction of Major Adverse Cardiovascular Events and Mortality after Primary Percutaneous Coronary Intervention"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7526-1641","authenticated-orcid":true,"given":"Lidija","family":"Savic","sequence":"first","affiliation":[{"name":"Coronary Care Unit, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"},{"name":"Cardiology Clinic, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Mrdovic","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"},{"name":"Cardiology Clinic, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milika","family":"Asanin","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"},{"name":"Cardiology Clinic, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0890-535X","authenticated-orcid":true,"given":"Sanja","family":"Stankovic","sequence":"additional","affiliation":[{"name":"Center for Medical Biochemistry, Emergency Hospital, Clinical Center of Serbia, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordana","family":"Krljanac","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"},{"name":"Cardiology Clinic, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratko","family":"Lasica","sequence":"additional","affiliation":[{"name":"Coronary Care Unit, Clinical Centre of Serbia, Emergency Hospital, Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2017.1256201"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.05.071"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.07.108"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.12.078"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-14-0808"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2459\/jcm.0b013e328339d910"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.2459\/jcm.0b013e328356a29c"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2011-300129"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.7754\/clin.lab.2015.150523"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-012-0276-z"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.118.008708"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.11.018"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.08.004"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.5603\/kp.a2013.0216"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2009.00476.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0123215"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.07.023"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy127"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000131765.73959.87"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.041"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.11.036"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004425"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.5603\/kp.a2018.0031"}],"container-title":["Journal 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