{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:35:10Z","timestamp":1747190110101,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,12,8]],"date-time":"2019-12-08T00:00:00Z","timestamp":1575763200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Vascular Medicine"],"published-print":{"date-parts":[[2019,12,8]]},"abstract":"<jats:p>Present literature demonstrates an equivocal relationship between testosterone and thrombogenicity. Herein, we describe a case in which a patient used an unspecified amount and duration of exogenous testosterone injections, subsequently developing thrombotic events in his: right radial artery, right iliac artery, superficial femoral artery, splenic artery and a bilateral lower lobe pulmonary embolism. As a result, clinicians should consider exogenous testosterone use as a potential risk factor when the etiology of a patient\u2019s thrombotic events are not clear. We also completed a literature review of the molecular mechanisms in which testosterone can increase the clot burden through an increases human platelet thromboxane A2 receptor density and an increase in erythropoiesis.<\/jats:p>","DOI":"10.1155\/2019\/3097865","type":"journal-article","created":{"date-parts":[[2019,12,8]],"date-time":"2019-12-08T18:30:18Z","timestamp":1575829818000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["A Tumultuous Course of Exogenous Testosterone by a Bodybuilder Causing a Catastrophic Hypercoagulable State in the Surgical Intensive Care Unit"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9962-1370","authenticated-orcid":true,"given":"Kevin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, The University of Toledo Medical Center, Toledo, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia","family":"Toraby","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Toledo Medical Center, Toledo, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Cotterman","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Toledo Medical Center, Toledo, OH, USA"},{"name":"Department of Critical Care and Trauma Surgery, ProMedica Toledo Hospital, Toledo, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babatunde","family":"Oriowo","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Toledo Medical Center, Toledo, OH, USA"},{"name":"Department of Vascular Surgery, ProMedica Toledo Hospital, Toledo, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Fish","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Toledo Medical Center, Toledo, OH, USA"},{"name":"Department of Vascular Surgery, ProMedica Toledo Hospital, Toledo, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4135\/978144627305014537438"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1210\/er.2013-1058"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2018.10.023"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.91.11.2742"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt154"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1545"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.09.061"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5968"}],"container-title":["Case Reports in Vascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crivam\/2019\/3097865.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crivam\/2019\/3097865.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crivam\/2019\/3097865.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,8]],"date-time":"2019-12-08T18:30:20Z","timestamp":1575829820000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crivam\/2019\/3097865\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,8]]},"references-count":8,"alternative-id":["3097865","3097865"],"URL":"https:\/\/doi.org\/10.1155\/2019\/3097865","relation":{},"ISSN":["2090-6986","2090-6994"],"issn-type":[{"type":"print","value":"2090-6986"},{"type":"electronic","value":"2090-6994"}],"subject":[],"published":{"date-parts":[[2019,12,8]]}}}