{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:50:12Z","timestamp":1780638612186,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T00:00:00Z","timestamp":1576800000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[2019,12,20]]},"abstract":"<jats:p><jats:italic>Acinetobacter baumannii<\/jats:italic>is an important opportunistic pathogen that shows resistance to cephalosporins, penicillins, carbapenems, fluoroquinolones, and aminoglycosides, the multiresistance being associated with its ability to form biofilms in clinical environments. The aim of this study was to determine biofilm formation and its potential association with genes involved in antibiotic resistance mechanisms of<jats:italic>A. baumannii<\/jats:italic>isolates of different clinical specimens. We demonstrated 100% of the<jats:italic>A. baumannii<\/jats:italic>isolates examined to be multidrug resistant (MDR), presenting a 73.3% susceptibility to cefepime and a 53.3% susceptibility to ciprofloxacin. All<jats:italic>A. baumannii<\/jats:italic>isolates were positive for<jats:italic>bla<\/jats:italic><jats:sub>OXA-51<\/jats:sub>, 33.3% being positive for<jats:italic>bla<\/jats:italic><jats:sub>OXA-23<\/jats:sub>and IS<jats:italic>Aba1<\/jats:italic>, and 73.3% being positive for<jats:italic>gyrA<\/jats:italic>. We found 86.6% of<jats:italic>A. baumannii<\/jats:italic>strains to be low-grade biofilm formers and 13.3% to be biofilm negative; culturing on Congo red agar (CRA) plates revealed that 73.3% of the<jats:italic>A. baumannii<\/jats:italic>isolates to be biofilm producers, while 26.6% were not. These properties, combined with the role of<jats:italic>A. baumannii<\/jats:italic>as a nosocomial pathogen, increase the probability of<jats:italic>A. baumannii<\/jats:italic>causing nosocomial infections and outbreaks as a complication during therapeutic treatments and emphasize the need to control<jats:italic>A. baumannii<\/jats:italic>biofilms in hospital environments.<\/jats:p>","DOI":"10.1155\/2019\/3454907","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T23:30:57Z","timestamp":1576884657000},"page":"1-5","source":"Crossref","is-referenced-by-count":27,"title":["Biofilm Formation and Detection of Fluoroquinolone- and Carbapenem-Resistant Genes in Multidrug-Resistant<i>Acinetobacter baumannii<\/i>"],"prefix":"10.1155","volume":"2019","author":[{"given":"Mar\u00eda-Guadalupe","family":"Avila-Novoa","sequence":"first","affiliation":[{"name":"Laboratorio de Alimentos, Departamento de Ciencias M\u00e9dicas y de la Vida, Divisi\u00f3n de Desarrollo Biotecnol\u00f3gico, Universidad de Guadalajara, Centro Universitario de la Ci\u00e9nega. 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