{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:32:53Z","timestamp":1762507973310,"version":"3.37.3"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T00:00:00Z","timestamp":1576540800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","award":["E26\/202.781\/2017","302401\/2016-4"],"award-info":[{"award-number":["E26\/202.781\/2017","302401\/2016-4"]}],"id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["E26\/202.781\/2017","302401\/2016-4"],"award-info":[{"award-number":["E26\/202.781\/2017","302401\/2016-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2019,12,17]]},"abstract":"<jats:p><jats:italic>Background and Aims<\/jats:italic>. Magnetic resonance enterography (MRE) has become an important modality of radiological imaging in the evaluation of Crohn\u2019s disease (CD). The aim of this study was to investigate the impact of MRE in the assessment of disease activity and abdominal complications and in the making of therapeutic decisions for patients with CD. <jats:italic>Methods<\/jats:italic>. In a cross-sectional retrospective study, we selected 74 patients with CD who underwent MRE and ileocolonoscopy with an interval between the two exams of up to 30 days between January 2011 and December 2017. We assessed the parameters of the images obtained by MRE and investigated the agreement with the level of disease activity and complications determined by a clinical evaluation, inflammatory biomarkers, and endoscopy, as well as the resulting changes in medical and surgical management. <jats:italic>Results<\/jats:italic>. Changes in medical management were detected in 41.9% of patients. Significant changes in medical decisions were observed in individuals with a purely penetrating (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.012<\/mml:mn><\/mml:math>) or a mixed (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.024<\/mml:mn><\/mml:math>) MRE pattern. Patients with normal MRE patterns had a correlation with unchanged medical decisions (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.001<\/mml:mn><\/mml:math>). There were statistically significant agreements between the absence of inflammatory criteria on MRE and remission according to the Harvey and Bradshaw index (HBI) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.037<\/mml:mn><\/mml:math>), the presence of inflammatory criteria on MRE and positive results for calprotectin (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.005<\/mml:mn><\/mml:math>), and penetrating criteria on MRE and the scoring endoscopic system for Crohn\u2019s disease (SES-CD), indicating active disease (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.048<\/mml:mn><\/mml:math>). Finally, there was significant agreement between the presence of fibrostenotic criteria and a long disease duration (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>.027<\/mml:mn><\/mml:math>). <jats:italic>Conclusion<\/jats:italic>. MRE discloses disease activity and complications not apparent with other modalities and results in changes in therapeutic decisions. In addition to being used for diagnosis, MRE should be routinely used in the follow-up of CD patients.<\/jats:p>","DOI":"10.1155\/2019\/3467316","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T18:30:40Z","timestamp":1576607440000},"page":"1-9","source":"Crossref","is-referenced-by-count":7,"title":["Changes in the Management of Patients with Crohn\u2019s Disease Based on Magnetic Resonance Enterography Patterns"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0942-5297","authenticated-orcid":true,"given":"Evelyn Sayuri S.","family":"Chinem","sequence":"first","affiliation":[{"name":"Disciplina de Gastroenterologia e Endoscopia Digestiva, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ 20551-900, Brazil"},{"name":"Servi\u00e7o de Gastroenterologia do Hospital Universit\u00e1rio Gaffree e Guinle, Rio de Janeiro, RJ 20270-901, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara C.","family":"Esberard","sequence":"additional","affiliation":[{"name":"Disciplina de Gastroenterologia e Endoscopia Digestiva, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ 20551-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre da L.","family":"Moreira","sequence":"additional","affiliation":[{"name":"Disciplina de Proctologia, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ 20551-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana G.","family":"Barbassa","sequence":"additional","affiliation":[{"name":"CDPI\/DASA (Cl\u00ednica de Diagno\u00f3stico por Imagem\/Diagn\u00f3stico das Am\u00e9ricas S\/A), Rio de Janeiro, RJ 22440-032, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme M.","family":"da Cunha","sequence":"additional","affiliation":[{"name":"CDPI\/DASA (Cl\u00ednica de Diagno\u00f3stico por Imagem\/Diagn\u00f3stico das Am\u00e9ricas S\/A), Rio de Janeiro, RJ 22440-032, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Jose de V.","family":"Carneiro","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia, Departamento de Cl\u00ednica M\u00e9dica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-913, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3647-7324","authenticated-orcid":true,"given":"Heitor S.","family":"de Souza","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia, Departamento de Cl\u00ednica M\u00e9dica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-913, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1127-0394","authenticated-orcid":true,"given":"Ana Teresa P.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Disciplina de Gastroenterologia e Endoscopia Digestiva, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ 20551-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001201"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2018.1503053"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.186"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000845"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000909"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2008.168"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308101"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.11.005"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200002000-00002"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2471070611"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04710.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw168"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2012.10.005"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2011.214"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000727"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2427"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.151415"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2323-0"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1667\/RR0554.1"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.68"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32835d4e9c"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2010.12.018"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(80)92767-1"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1287-0"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2523082167"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000244"},{"issue":"5","key":"27","first-page":"293","volume":"17","year":"2015","journal-title":"Israel Medical Association Journal"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.4321\/s1130-01082012001100005"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.09.056"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000816"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2017.464"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2018.16.3.445"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-016-0878-5"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000404"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx156"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-3010-z"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i21.2279"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2483261"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0212404"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200207000-00002"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.01.055"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.6.777"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1781-0"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.carj.2016.02.004"}],"container-title":["Gastroenterology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2019\/3467316.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2019\/3467316.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2019\/3467316.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T18:30:42Z","timestamp":1576607442000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/grp\/2019\/3467316\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,17]]},"references-count":44,"alternative-id":["3467316","3467316"],"URL":"https:\/\/doi.org\/10.1155\/2019\/3467316","relation":{},"ISSN":["1687-6121","1687-630X"],"issn-type":[{"type":"print","value":"1687-6121"},{"type":"electronic","value":"1687-630X"}],"subject":[],"published":{"date-parts":[[2019,12,17]]}}}