{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T05:23:06Z","timestamp":1748496186928,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2019,2,20]]},"abstract":"<jats:p>Cutaneous involvement by precursor T-cell lymphoblastic leukemia\/lymphoma (T-ALL\/LBL) is rare, and almost all cases are seen in association with bone marrow, blood, and\/or lymph node involvement. Presentation with isolated skin involvement is very rare. Literature review revealed only one case report of primary cutaneous T-cell LBL. We discuss here another patient diagnosed with primary cutaneous T-cell LBL at our institute. This patient was initially misdiagnosed as having peripheral T-cell lymphoma NOS. Cytogenetic analysis showed the CDKN2A deletion (\u22129p21\u00d72) in addition to three intact copies of ABL1 (+9q34). Although she failed multiple lines of intensive chemotherapy, her disease remained confined to the skin. We believe that this presentation of T-LBL is underreported, and many patients are likely misdiagnosed as having high-grade cutaneous T-cell lymphomas. With this case and literature review, we would like to highlight the importance of keeping lymphoblastic lymphoma on the differential diagnosis of cutaneous T-cell lymphoma-like lesions to avoid delay in diagnosis and inappropriate treatment of this aggressive disease.<\/jats:p>","DOI":"10.1155\/2019\/3540487","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T18:36:19Z","timestamp":1550687779000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["Primary Cutaneous T-Cell Lymphoblastic Lymphoma: Case Report and Literature Review"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5483-7947","authenticated-orcid":true,"given":"Sharad","family":"Khurana","sequence":"first","affiliation":[{"name":"Mayo Clinic, Jacksonville, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8585-4790","authenticated-orcid":true,"given":"Manuel","family":"Beltran","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Jacksonville, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liuyan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Jacksonville, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernesto","family":"Ayala","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Jacksonville, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5950-4620","authenticated-orcid":true,"given":"Vivek","family":"Roy","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Jacksonville, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4065\/80.11.1517"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.10.020"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1309\/q5gv-3k00-wac6-bbub"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1542\/peds.100.1.60"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2011.618233"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21442"},{"issue":"1","key":"7","first-page":"23","volume":"7","year":"2005","journal-title":"MedGenMed"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1159\/000245966"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(91)70302-i"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-08-231217"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.08788.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergencyto.2009.01.002"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2017.01.001"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v3.i8.727"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/dad.0b013e3181b3aa1c"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-010-0007-5"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1999.tb01861.x"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2010.12.003"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2017.04.002"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2019\/3540487.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2019\/3540487.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2019\/3540487.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T18:36:21Z","timestamp":1550687781000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crihem\/2019\/3540487\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,20]]},"references-count":19,"alternative-id":["3540487","3540487"],"URL":"https:\/\/doi.org\/10.1155\/2019\/3540487","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"type":"print","value":"2090-6560"},{"type":"electronic","value":"2090-6579"}],"subject":[],"published":{"date-parts":[[2019,2,20]]}}}