{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T15:50:47Z","timestamp":1781797847478,"version":"3.54.5"},"reference-count":11,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:00:00Z","timestamp":1559433600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurology Research International"],"published-print":{"date-parts":[[2019,6,2]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Guillain-Barre syndrome is the most common cause of acute flaccid paralysis in the adult population. It occurs at the rate of 0.34 to 4 per 100000 individuals. This study was conducted to determine the clinicoepidemiological profile and outcome of the patients with Guillain-Barre syndrome.<jats:italic> Materials and Methods<\/jats:italic>. We conducted a retrospective study of patients with Guillain-Barre syndrome, presented at B.P. Koirala Institute of Health Sciences, a tertiary care centre in eastern Nepal, from January 2013 to December 2017. All patients diagnosed with Guillain-Barre syndrome were included in this study. The handwritten case record files of the study population were retrieved from medical record section of the institute.<jats:italic> Results<\/jats:italic>. Of 31 patients with Guillain-Barre syndrome, the mean age of patients was 17\u00b112 years. The most common presenting symptom of study population was ascending paralysis (93.5%). Respiratory failure requiring mechanical ventilation occurred in 16.1%. The common variants are AIDP and AMAN. Respiratory tract infection (29%) was the most common antecedent event. The in-hospital mortality of Guillain-Barre syndrome was 6.45%.<jats:italic> Conclusion<\/jats:italic>. Guillain-Barre syndrome is commonly seen in the young population. The most common symptom of Guillain-Barre syndrome was ascending paralysis. The in-hospital mortality rate of patients with GBS was 6.45%.<\/jats:p>","DOI":"10.1155\/2019\/3867946","type":"journal-article","created":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T19:33:18Z","timestamp":1559503998000},"page":"1-5","source":"Crossref","is-referenced-by-count":9,"title":["Clinical Profile, Functional Outcome, and Mortality of Guillain-Barre Syndrome: A Five-Year Tertiary Care Experience from Nepal"],"prefix":"10.1155","volume":"2019","author":[{"given":"Saroj Kumar","family":"Bhagat","sequence":"first","affiliation":[{"name":"B.P. Koirala Institute of Health Sciences, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrey","family":"Sidhant","sequence":"additional","affiliation":[{"name":"B.P. Koirala Institute of Health Sciences, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukesh","family":"Bhatta","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine, B.P. Koirala Institute of Health Sciences, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Ghimire","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Critical Care, B.P. Koirala Institute of Health Sciences, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4370-0464","authenticated-orcid":true,"given":"Bhupendra","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, B.P. Koirala Institute of Health Sciences, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0704(05)70293-1"},{"issue":"1","key":"2","first-page":"14","volume":"10","year":"2013","journal-title":"Nepal Journal of Neuroscience"},{"issue":"1","key":"3","first-page":"50","volume":"10","year":"2014","journal-title":"Journal of Armed Forces Medical College, Bangladesh"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcv190"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.09.123"},{"key":"6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12883-016-0787-9","volume":"17","year":"2017","journal-title":"BMC Neurology"},{"key":"7","first-page":"1","volume":"96","year":"2017","journal-title":"Medicine"},{"issue":"11","key":"8","first-page":"2003","volume":"55","year":"2005","journal-title":"Journal of the Pakistan Medical Association"},{"issue":"2","key":"9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3126\/jnps.v31i2.4065","volume":"31","year":"2011","journal-title":"Journal of Nepal Paediatric Society"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000310983.38724.d4"},{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1136\/jnnp.64.1.74","volume":"64","year":"1998","journal-title":"Neurol Neurosurg Psychiatry"}],"container-title":["Neurology Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/nri\/2019\/3867946.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/nri\/2019\/3867946.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/nri\/2019\/3867946.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T19:33:21Z","timestamp":1559504001000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/nri\/2019\/3867946\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,2]]},"references-count":11,"alternative-id":["3867946","3867946"],"URL":"https:\/\/doi.org\/10.1155\/2019\/3867946","relation":{},"ISSN":["2090-1852","2090-1860"],"issn-type":[{"value":"2090-1852","type":"print"},{"value":"2090-1860","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,2]]}}}