{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:49:45Z","timestamp":1740156585887,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T00:00:00Z","timestamp":1575849600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Mars Cardio Association"},{"DOI":"10.13039\/100007586","name":"Aix-Marseille Universit\u00e9","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007586","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology Research and Practice"],"published-print":{"date-parts":[[2019,12,9]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Cardiogenic shock (CS) remains a major challenge in contemporary cardiology. Data regarding CS etiologies and their prognosis are limited and mainly derived from tertiary referral centers. <jats:italic>Aims<\/jats:italic>. To investigate the current etiologies of cardiogenic shock and their associated short- and long-term outcomes in a secondary center without surgical back-up. <jats:italic>Methods<\/jats:italic>. We performed an observational prospective monocenter study. All patients admitted for a first episode of CS related to left ventricular dysfunction were enrolled. The definition of CS was consistent with the European Society of Cardiology guidelines. Patients were followed for 6 months. Etiologies were analyzed, and survival rates derived from Kaplan-Meier estimates were compared with the log-rank test. <jats:italic>Results<\/jats:italic>. Between January 2015 and January 2016, 152 patients were included. The first most common cause of CS was acute decompensation of chronic heart failure (CHF). Acute coronary syndromes (ACS) were the second most common cause of CS (35.4%). At one month, the all-cause mortality rate was 39.5% and was similar between ACS and CHF (43% vs 35%, respectively; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.7<\/mml:mn><\/mml:mrow><\/mml:math>). In a landmark analysis between 1 and 6 months, we observed a significantly higher mortality in patients with CHF than in patients with ACS (18% vs. 0%; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:mrow><\/mml:math>). <jats:italic>Conclusions<\/jats:italic>. In the present registry, acute decompensation of chronic heart failure was the most common cause of CS, while ACS complicated by CS was the second most common cause. Of importance, acute decompensation of CHF was associated with a significantly worse outcome than ACS in the long term.<\/jats:p>","DOI":"10.1155\/2019\/3869603","type":"journal-article","created":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T18:31:31Z","timestamp":1575916291000},"page":"1-7","source":"Crossref","is-referenced-by-count":3,"title":["Etiology and Prognosis of Cardiogenic Shock in a Secondary Center without Surgical Back-Up"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3573-0244","authenticated-orcid":true,"given":"Laurent","family":"Bonello","sequence":"first","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Laine","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etienne","family":"Puymirat","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Cardiologie, H\u00f4pital Europ\u00e9en Georges Pompidou, Assistance Publique des H\u00f4pitaux de Paris, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Ceccaldi","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e9lanie","family":"Gaubert","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franck","family":"Paganelli","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pr Franck","family":"Thuny","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thibaut","family":"Dabry","sequence":"additional","affiliation":[{"name":"Assistance Publique-H\u00f4pitaux de Marseille, Intensice Care Unit, H\u00f4pital Nord, Marseille, France"},{"name":"Mediterranean Academic Association for Research and Studies in Cardiology (MARS Cardio), Marseille, France"},{"name":"Aix-Marseille University, INSERM UMRS 1076, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Schurtz","sequence":"additional","affiliation":[{"name":"USIC et Centre H\u00e9modynamique, Institut C\u0153ur Poumon, Centre Hospitalier R\u00e9gional et Universitaire de Lille, Facult\u00e9 de M\u00e9decine de l\u2019Universit\u00e9 de Lille, INSERM UMR1011, Lille F-59000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clement","family":"Delmas","sequence":"additional","affiliation":[{"name":"Intensive Cardiac Care Unit, Rangueil University Hospital, Toulouse, France"},{"name":"Institute of Metabolic and Cardiovascular Diseases (I2MC), Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), UMR-1048, Toulouse, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Mancini","sequence":"additional","affiliation":[{"name":"Aix-Marseille Univ, INSERM, IRD, UMR912, SESSTIM, \u201cCancers Biomedicine & Society\u201d Group, Marseille, France"},{"name":"APHM, Timone Hospital, Public Health Department (BIOSTIC), Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Lemesle","sequence":"additional","affiliation":[{"name":"USIC et Centre H\u00e9modynamique, Institut C\u0153ur Poumon, Centre Hospitalier R\u00e9gional et Universitaire de Lille, Facult\u00e9 de M\u00e9decine de l\u2019Universit\u00e9 de Lille, INSERM UMR1011, Lille F-59000, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.646"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-018-5222-9"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.260"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-16-0125"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.030798"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.07.074"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.03.012"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1808788"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2018.03.008"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-9-200811040-00005"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1001\/2012.jama.11348"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409077"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.04.101"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(11)60101-3"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1703374"}],"container-title":["Cardiology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crp\/2019\/3869603.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crp\/2019\/3869603.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crp\/2019\/3869603.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T18:31:33Z","timestamp":1575916293000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crp\/2019\/3869603\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,9]]},"references-count":15,"alternative-id":["3869603","3869603"],"URL":"https:\/\/doi.org\/10.1155\/2019\/3869603","relation":{},"ISSN":["2090-8016","2090-0597"],"issn-type":[{"type":"print","value":"2090-8016"},{"type":"electronic","value":"2090-0597"}],"subject":[],"published":{"date-parts":[[2019,12,9]]}}}