{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:00:17Z","timestamp":1760122817950,"version":"3.37.3"},"reference-count":43,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T00:00:00Z","timestamp":1547942400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000001","name":"Alberta Cancer Foundation","doi-asserted-by":"publisher","award":["#24404","#2011\u2013701000"],"award-info":[{"award-number":["#24404","#2011\u2013701000"]}],"id":[{"id":"10.13039\/501100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000521","name":"Canadian Cancer Society","doi-asserted-by":"publisher","award":["#24404","#2011\u2013701000"],"award-info":[{"award-number":["#24404","#2011\u2013701000"]}],"id":[{"id":"10.13039\/501100000521","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs","doi-asserted-by":"publisher","award":["#24404","#2011\u2013701000"],"award-info":[{"award-number":["#24404","#2011\u2013701000"]}],"id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Obesity"],"published-print":{"date-parts":[[2019,1,20]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Exercise interventions can result in weight loss, which is associated with reductions in disease risk. It is unknown how the volume of exercise prescribed in a one-time exercise intervention impacts long-term body fatness. We compared 24-month body fat changes among postmenopausal women previously prescribed 300 versus 150 minutes\/week of exercise in a year-long exercise intervention trial. <jats:italic>Methods<\/jats:italic>. The Breast Cancer and Exercise Trial in Alberta (BETA) was a two-centred randomized controlled trial in Alberta, Canada. The trial consisted of a 12-month intervention and 12-month observation period. For the intervention, participants were randomized to either a moderate-volume exercise group (150\u2009min\/week) or a high-volume exercise group (300\u2009min\/week). Participants in this study were 334 inactive postmenopausal women who had been followed-up to 24 months. The primary outcome for this study was 24-month change in total body fat using dual energy X-ray absorptiometry scans. Other measures included weight, waist and hip circumferences, subcutaneous and intra-abdominal fat from computed tomography scans, and lean mass. Researchers were blinded to randomization group when measuring body fat. <jats:italic>Results<\/jats:italic>. Both groups self-reported \u223c180 minutes\/week moderate\u2013vigorous activity at 24 months. No statistically significant difference was found in total body fat at 24 months between the two groups. Statistically significant effects (comparing high versus moderate groups) were found for BMI (least-square mean change (95% CI): \u22120.66 (\u22120.97, \u22120.36) versus \u22120.25 (\u22120.55, 0.05) kg\/m<jats:sup>2<\/jats:sup>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.04<\/mml:mn><\/mml:mrow><\/mml:math>), waist-to-hip ratio (\u22120.033 (\u22120.040, \u22120.026) versus \u22120.023 (\u22120.030, \u22120.016), <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:mrow><\/mml:math>), and subcutaneous abdominal fat area (\u221232.18 (\u221239.30, \u221225.06) versus \u221222.20 (\u221229.34, \u221215.05) cm<jats:sup>2<\/jats:sup>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.04<\/mml:mn><\/mml:mrow><\/mml:math>). <jats:italic>Conclusion<\/jats:italic>. Prescribing 300 versus 150 minutes\/week of exercise to inactive postmenopausal women resulted in some long-term greater decreases in measures of body composition but no overall differences in total body fat loss. This trail is registered with <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT01435005\">NCT01435005<\/jats:ext-link>.<\/jats:p>","DOI":"10.1155\/2019\/3916416","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T18:31:09Z","timestamp":1548009069000},"page":"1-11","source":"Crossref","is-referenced-by-count":5,"title":["Exercise Dose Effects on Body Fat 12 Months after an Exercise Intervention: Follow-up from a Randomized Controlled Trial"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4783-1966","authenticated-orcid":true,"given":"Christine M.","family":"Friedenreich","sequence":"first","affiliation":[{"name":"Department of Cancer Epidemiology and Prevention Research, CancerControl Alberta, Alberta Health Services, Calgary, Alberta, Canada"},{"name":"Departments of Oncology and Community Health Sciences, Cumming 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