{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T13:36:59Z","timestamp":1792503419914,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T00:00:00Z","timestamp":1553644800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Health, Community Development, Gender, Elderly and Children"},{"name":"CUHAS"},{"DOI":"10.13039\/100008459","name":"University of Calgary","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008459","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2019,3,27]]},"abstract":"<jats:p>Urinary tract infection (UTI) and preeclampsia are common among pregnant women and are associated with adverse maternal-fetal and neonatal outcomes. Despite this, limited information exists on the association between UTIs and preeclampsia in Tanzania to guide specific management and thereby averting the adverse outcomes. A 1:2 matched case-control study (by age and gravidity) involving 131 pregnant women with preeclampsia (cases) and 262 without preeclampsia (controls) was conducted. Sociodemographic and clinical information was collected using a questionnaire. Midstream urine samples were collected during admission for culture and antimicrobial susceptibility testing (AST). Out of 393 pregnant women enrolled, 110 (28.0%), 95% CI: 23.8%-32.7%, had significant bacteriuria [cases: 50.4% (66\/131) and control: 16.8% (44\/262)]. Pregnant women with preeclampsia had 7.7 odds of having significant bacteriuria than those without preeclampsia [OR=7.7, 95% CI (4.11-14.49); p-value &lt;0.001].<jats:italic> Escherichia coli<\/jats:italic>, 50 (45.5%), and<jats:italic> Klebsiella <\/jats:italic>spp., 25 (23.6%), predominated, and resistance to gentamicin, ceftriaxone, and piperacillin-tazobactam ranged from 9.0% to 29.0% in these dominant species. Extended spectrum beta lactamases (ESBL) production in<jats:italic> Escherichia coli<\/jats:italic> and<jats:italic> Klebsiella<\/jats:italic> spp. was 18.0% (9\/50) and 15.4% (4\/26), respectively. Routine urine culture and AST among pregnant women with preeclampsia should be introduced in the antenatal clinics to ensure prompt management. Delineation of maternal-fetal and neonatal outcomes among pregnant women with preeclampsia and UTIs would be of interest in future studies.<\/jats:p>","DOI":"10.1155\/2019\/3937812","type":"journal-article","created":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T19:36:18Z","timestamp":1553715378000},"page":"1-8","source":"Crossref","is-referenced-by-count":36,"title":["Urinary Tract Infections and Preeclampsia among Pregnant Women Attending Two Hospitals in Mwanza City, Tanzania: A 1:2 Matched Case-Control Study"],"prefix":"10.1155","volume":"2019","author":[{"given":"Joshua","family":"Kaduma","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Bugando Medical Centre and Catholic University of Health and Allied Sciences, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2420-5329","authenticated-orcid":true,"given":"Jeremiah","family":"Seni","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Weill-Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clotilda","family":"Chuma","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Bugando Medical Centre and Catholic University of Health and Allied Sciences, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Kirita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Sekou Toure Regional Referral Hospital, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fridolin","family":"Mujuni","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Bugando Medical Centre and Catholic University of Health and Allied Sciences, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3511-2523","authenticated-orcid":true,"given":"Martha F.","family":"Mushi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Weill-Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"van der Meer","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine: Ecosystem and Public Health, University of Calgary, Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7526-6271","authenticated-orcid":true,"given":"Stephen E.","family":"Mshana","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Weill-Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2013.39202"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6968.12204"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1080\/00365540410021045"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(02)01054-9"},{"issue":"3","key":"5","first-page":"154","volume":"11","year":"2009","journal-title":"Tanzania Journal of Health 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