{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:14:06Z","timestamp":1792689246141,"version":"4.5.0"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T00:00:00Z","timestamp":1573430400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2019,11,11]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. To evaluate the feasibility and applicability of using office hysteroscopy in women with intact hymen. <jats:italic>Methods. <\/jats:italic>We recruited 836 patients with intact hymen with different indications who underwent diagnostic hysteroscopy without anesthesia in an outpatient setting from 2007 to 2016 at Chang Gung Memorial Hospital at Linkou. <jats:italic>Results. <\/jats:italic>Patients\u2019 mean age was 35\u2009\u00b1\u200910.6 years (range 3\u201369 years). Most patients (86.4%) with postmenopausal bleeding had intrauterine lesions, and they were especially at high risk (50%) for endometrial hyperplasia or malignancy. Five hundred thirty (63.3%) patients had histologic findings confirming concordance between hysteroscopic and histologic findings. Submucosal myoma had the highest concordance (96.3%), whereas endometrial hyperplasia had the lowest concordance (50%). Forty-eight patients (5.7%) had endometrial hyperplasia, and 35 patients (4.2%) had endometrial malignancy. Two patients who were thought to have nonspecific endometrial thickening actually had endometrial pathology. <jats:italic>Conclusions. <\/jats:italic>Hysteroscopy through vaginoscopic approach is feasible and well-tolerated in the patients with intact hymen. This outpatient procedure provides accurate evaluation of lesions of the genital tract and should be considered in patients without a history of intercourse.<\/jats:p>","DOI":"10.1155\/2019\/4074975","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T18:32:42Z","timestamp":1573497162000},"page":"1-5","source":"Crossref","is-referenced-by-count":7,"title":["Office Hysteroscopy as a Valid Tool for Diagnosis of Genital Tract Lesions in Females with Intact Hymen"],"prefix":"10.1155","volume":"2019","author":[{"given":"Hui-Yu","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Taipei, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ting","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Yun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan"},{"name":"Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Ying","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"Hsuan Weng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5730-6551","authenticated-orcid":true,"given":"Chin-Jung","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan"},{"name":"Chang Gung University College of Medicine, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2014.09.006"},{"issue":"3","key":"2","first-page":"256","volume":"30","year":"2007","journal-title":"Chang Gung Medical Journal"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(97)80019-9"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000227750.93984.06"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02503.x"},{"key":"6","first-page":"1251","volume-title":"Uterine 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