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Previous studies have shown variable efficacy for osseous sarcoidosis utilizing multiple agents alone or in combination, often using imaging follow-up in conjunction with clinical assessment to evaluate response to treatment. We present a case of widespread skeletal involvement of sarcoidosis without evidence of concurrent pulmonary disease demonstrating marked clinical improvement and near-complete resolution of imaging abnormalities on magnetic resonance imaging (MRI) following the use of methotrexate as the primary pharmacologic agent.<\/jats:p>","DOI":"10.1155\/2019\/4156313","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T18:31:00Z","timestamp":1573497060000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Resolution of Osseous Sarcoidosis with Methotrexate"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1619-4925","authenticated-orcid":true,"given":"Christopher","family":"Kanner","sequence":"first","affiliation":[{"name":"University of Vermont Medical Center, The Robert Larner, M. D. 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