{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:58:05Z","timestamp":1765727885721,"version":"3.37.3"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T00:00:00Z","timestamp":1573430400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Capital\u2019s Funds for Health Improvement and Research","award":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"],"award-info":[{"award-number":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"]}]},{"name":"Capital\u2019s Funds for Health Improvement and Research","award":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"],"award-info":[{"award-number":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"]}]},{"DOI":"10.13039\/501100009592","name":"Beijing Municipal Science and Technology Commission","doi-asserted-by":"publisher","award":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"],"award-info":[{"award-number":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beijing Municipal Training Foundation for Highly Qualified and Technological Talents of Health System","award":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"],"award-info":[{"award-number":["2016-1-2057","2016-2-2054","Z151100004015021","2014-3-013"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2019,11,11]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Neck circumference (NC) was found to be related to the risk factors of cardiovascular disease. However, the effects of NC on cardiovascular disease are still controversial. A prospective study of Chinese patients with type 2 diabetes was performed to evaluate the relationship between NC and cardiovascular disease. <jats:italic>Methods<\/jats:italic>. A multicenter prospective study with eight-year follow-up was conducted in Beijing communities. Cardiovascular events were defined as myocardial infarction, unstable angina pectoris, hospitalization for heart failure, coronary revascularization, cardiac death, stroke, transient ischemic attack, and cerebral hemorrhage. <jats:italic>Results<\/jats:italic>. A total of 3,009 diabetic patients were recruited. Following an eight-year follow-up, 211 patients with cardiovascular events (105 in men and 106 in women) were identified. All patients were categorized into two groups according to the upper quartile of NC (43\u2009cm in men and 39\u2009cm in women). The prevalence of cardiovascular events in men with an NC\u2009&gt;43\u2009cm (16.48%) was higher than that in the group with an NC\u2009&lt;43\u2009cm (8.16%, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.007<\/mml:mn><\/mml:mrow><\/mml:math>). The prevalence of cardiovascular events in women with the NC\u2009&gt;39\u2009cm (10.67%) was higher compared to the group with NC\u2009&lt;39\u2009cm (5.31%, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.004<\/mml:mn><\/mml:mrow><\/mml:math>). The longitudinal prevalence of cardiovascular events in groups with different NC increased with the increasing duration of follow-up (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>). Cox regression analysis showed that higher NC was associated with the occurrence of cardiovascular events after adjusting for confounding variables (adjusted HR\u2009=\u20092.305 (1.535\u20133.460)). <jats:italic>Conclusions<\/jats:italic>. NC was associated with the occurrence of cardiovascular events in type 2 diabetes in Chinese communities, and greater NC may increase the risk of cardiovascular events by about 2.3-fold.<\/jats:p>","DOI":"10.1155\/2019\/4242304","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T18:31:02Z","timestamp":1573497062000},"page":"1-6","source":"Crossref","is-referenced-by-count":21,"title":["Association between Neck Circumference and the Occurrence of Cardiovascular Events in Type 2 Diabetes: Beijing Community Diabetes Study 20 (BCDS-20)"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2919-5564","authenticated-orcid":true,"given":"Guang-Ran","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Xia","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Medical Records and Statistics, Beijing Ditan Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Lian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han-Jing","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2709-5287","authenticated-orcid":true,"given":"Shen-Yuan","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang-Xiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong-Rong","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Dong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jinsong Community Health Service Center, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Ling","family":"Li","sequence":"additional","affiliation":[{"name":"Xinjiekou Community Health Service Center, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Hua","family":"Sun","sequence":"additional","affiliation":[{"name":"Cuigezhuang Community Health Service Center, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin-Fang","family":"Dai","sequence":"additional","affiliation":[{"name":"Yuetan Community Health Service Center of Fuxing Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da-Yong","family":"Gao","sequence":"additional","affiliation":[{"name":"Aerospace Central Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Li","family":"Cui","sequence":"additional","affiliation":[{"name":"Sanlitun Community Health Service Center, 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