{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:50:54Z","timestamp":1756385454657,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T00:00:00Z","timestamp":1569110400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2019,9,22]]},"abstract":"<jats:p>Jaundice, conjunctival hyperemia, and acute kidney injury (AKI) are the characteristics of leptospirosis. However, it is not well known that <jats:italic>Fusobacterium necrophorum<\/jats:italic> infection can have a clinical picture similar to that of leptospirosis. A 38-year-old man was admitted with jaundice, conjunctival hyperemia, and AKI for 7 days. Chest CT scan showed multiple pulmonary nodules, atypical for leptospirosis. We started treatment with IV piperacillin-tazobactam and minocycline. He became anuric and was urgently started on hemodialysis on the second hospital day. Later on, blood cultures grew <jats:italic>Fusobacterium necrophorum<\/jats:italic> and other anaerobic bacteria. Antibody and PCR assays for <jats:italic>Leptospira<\/jats:italic> were negative. We narrowed the antibiotics to IV ceftriaxone and metronidazole. He responded well to the treatment and was discharged on the 18th hospital day. <jats:italic>F. necrophorum<\/jats:italic> infection is known to cause mixed infection with other anaerobic bacteria. The resistance of many anaerobic bacteria continues to progress, and <jats:italic>F. necrophorum<\/jats:italic> itself sometimes produces <jats:italic>\u03b2<\/jats:italic>-lactamase. This case highlights the potential risks of using penicillin before diagnosis of leptospirosis.<\/jats:p>","DOI":"10.1155\/2019\/4380429","type":"journal-article","created":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T19:30:57Z","timestamp":1569180657000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["A Case of <i>Fusobacterium necrophorum<\/i> without Lemierre\u2019s Syndrome Mimicking Acute Leptospirosis"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1864-9724","authenticated-orcid":true,"given":"Ryo","family":"Yasuhara","sequence":"first","affiliation":[{"name":"Tokyo Medical and Dental University Hospital Faculty of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6232-3073","authenticated-orcid":true,"given":"Shunichi","family":"Shibazaki","sequence":"additional","affiliation":[{"name":"Department of Emergency and General Internal Medicine, Hitachinaka General Hospital, Hitachinaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayoshi","family":"Yamanouchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hitachinaka General Hospital, Hitachinaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1586\/eci.12.110"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2008.06.007"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(46)91055-0"},{"issue":"7","key":"4","first-page":"161","volume":"69","year":"2010","journal-title":"Hawaii Medical Journal"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.029942-0"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2014.11.013"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1177\/000348949410300307"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03474.x"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1086\/324084"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.00011-07"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/s0196-0644(05)80216-1"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-151-11-200912010-00011"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198903000-00002"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200211000-00006"},{"issue":"5","key":"15","first-page":"384","volume":"8","year":"1995","journal-title":"The Journal of the American Board of Family Practice"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21480"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2005.11.003"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-03-278127"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-51-3-269"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1086\/375226"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1086\/425001"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2019\/4380429.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2019\/4380429.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2019\/4380429.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,22]],"date-time":"2019-09-22T19:30:58Z","timestamp":1569180658000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criid\/2019\/4380429\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,22]]},"references-count":21,"alternative-id":["4380429","4380429"],"URL":"https:\/\/doi.org\/10.1155\/2019\/4380429","relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"type":"print","value":"2090-6625"},{"type":"electronic","value":"2090-6633"}],"subject":[],"published":{"date-parts":[[2019,9,22]]}}}