{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:49:29Z","timestamp":1790016569426,"version":"4.0.1"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T00:00:00Z","timestamp":1575590400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2019,12,6]]},"abstract":"<jats:p>Metastatic carcinomatosis to the liver is a pattern of malignant infiltration that tends to provoke hepatic fibrosis. It is a rare complication of multiple solid tumor types and often seen in the absence of discrete tumor mass in the liver. We report a case of a 69-year-old woman with metastatic ductal carcinoma of the breast who presented with rising serum tumor markers and mildly cirrhotic contour of the liver on a CT scan. An early diagnosis of occult spread to the liver was made by means of a percutaneous liver biopsy showing desmoplastic response to invasive breast cancer cells found diffusely in the liver. This case highlights a rare pattern of metastatic spread of breast cancer as well as predisposing and prognostic features.<\/jats:p>","DOI":"10.1155\/2019\/4935615","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T18:33:20Z","timestamp":1575657200000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["Radiographically Occult Carcinomatous Spread of Breast Cancer to the Liver: A Challenging Case"],"prefix":"10.1155","volume":"2019","author":[{"given":"Trish","family":"Millard","sequence":"first","affiliation":[{"name":"Division of Hematology\/Oncology, University of Virginia, 1215 Lee St, Charlottesville, VA 22908, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akriti","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Virginia, 1215 Lee St, Charlottesville, VA 22908, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiana","family":"Brenin","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, University of Virginia, 1215 Lee St, Charlottesville, VA 22908, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Marshall","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, University of Virginia, 1215 Lee St, Charlottesville, VA 22908, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0622-725X","authenticated-orcid":true,"given":"Patrick","family":"Dillon","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology, University of Virginia, 1215 Lee St, Charlottesville, VA 22908, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"2","key":"1","first-page":"113","volume":"6","year":"1975","journal-title":"CRC Critical Reviews in Clinical Radiology and Nuclear Medicine"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2013.1165"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1177\/030089160008600512"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-013-2943-z"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197502)35:2<445::aid-cncr2820350222>3.0.co;2-g"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2009.10.004"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700690128"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.09.3409"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1043\/1543-2165(2004)128<1418:Rodihm>2.0.Co;2"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-4-112"},{"issue":"1","key":"11","first-page":"62","volume":"7","year":"2011","journal-title":"Gastroenterology & hepatology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2015-214120"},{"issue":"5","key":"13","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/S1665-2681(19)31329-8","volume":"12","year":"2013","journal-title":"Annals of Hepatology"},{"issue":"7-8","key":"14","first-page":"273","volume":"38","year":"1984","journal-title":"The British Journal of Clinical Practice"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i15.2360"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2211001754"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-9332-9"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.03.049"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.9715"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.3876"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2019\/4935615.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2019\/4935615.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2019\/4935615.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T18:33:22Z","timestamp":1575657202000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crionm\/2019\/4935615\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,6]]},"references-count":20,"alternative-id":["4935615","4935615"],"URL":"https:\/\/doi.org\/10.1155\/2019\/4935615","relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"value":"2090-6706","type":"print"},{"value":"2090-6714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,6]]}}}