{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T20:20:40Z","timestamp":1767730840973,"version":"build-2238731810"},"reference-count":57,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2019,5,6]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Temporomandibular joint dysfunction (TMD) therapy remains an open challenge for modern dentistry. Herein, we propose a new neuromuscular lingual device able to reduce signs and symptoms of TMD in female patients with chronic orofacial pain.\n                    <jats:italic>Methods<\/jats:italic>\n                    . 50 females with myofascial TMD according to RDC\/TMD were randomly assigned to study (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200925) and control groups (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200925). At T0, both groups received sEMG\/KNG and pain evaluation by the VAS scale. The study group received the ELIBA device (lingual elevator by Balercia) constructed under ULF-TENS (ultra-low-frequency transcoutaneous electrical nervous stimulation). Subjects were instructed to use ELIBA at least for 16\u2009h\/day. After 6\u2009months (T1), both groups underwent to sEMG\/KNG and VAS revaluation.\n                    <jats:italic>Results<\/jats:italic>\n                    . T1 study group compared to controls showed a significant reduction in total (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mrow>\n                        <mml:mi>p<\/mml:mi>\n                        <mml:mo>&lt;<\/mml:mo>\n                        <mml:mn>0.0001<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) and mean (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mrow>\n                        <mml:mi>p<\/mml:mi>\n                        <mml:mo>&lt;<\/mml:mo>\n                        <mml:mn>0.0001<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) sEMG values, as well as a significant increase in both maximum vertical mouth opening (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mrow>\n                        <mml:mi>p<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>0.003<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) and maximum velocity in mouth opening (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mrow>\n                        <mml:mi>p<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>0.003<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) and closing (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                      <mml:mrow>\n                        <mml:mi>p<\/mml:mi>\n                        <mml:mo>&lt;<\/mml:mo>\n                        <mml:mn>0.0001<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). Interestingly, a significant reduction in pain measured by VAS (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                      <mml:mrow>\n                        <mml:mi>p<\/mml:mi>\n                        <mml:mo>&lt;<\/mml:mo>\n                        <mml:mn>0.0001<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) was reported.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . After 6\u2009months, the ELIBA device is able to significantly reduce TMD-associated myogenous pain and to promote the enhancement of sEMG\/KNG values.\n                    <jats:italic>Practical Implications<\/jats:italic>\n                    . ELIBA can be considered as a new device, potentially useful for head-neck pain relief in patients suffering from chronic TMD. In addition, its use promotes a muscles relaxation inducing freeway space increase. This characteristic makes it particularly useful for rehabilitation of patients with not enough space for construction of conventional orthotics or neuromuscular bites.\n                  <\/jats:p>","DOI":"10.1155\/2019\/5646143","type":"journal-article","created":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T14:52:23Z","timestamp":1557240743000},"page":"1-10","source":"Crossref","is-referenced-by-count":8,"title":["A Device Improves Signs and Symptoms of TMD"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9567-4459","authenticated-orcid":true,"given":"Annalisa","family":"Monaco","sequence":"first","affiliation":[{"name":"University of L\u2019Aquila, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, Building Delta 6\u2013Unit of Dentistry, V.le San Salvatore, L\u2019Aquila 67100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9585-1809","authenticated-orcid":true,"given":"Davide","family":"Pietropaoli","sequence":"additional","affiliation":[{"name":"University of L\u2019Aquila, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, Building Delta 6\u2013Unit of Dentistry, V.le San Salvatore, L\u2019Aquila 67100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"IAPNOR","sequence":"additional","affiliation":[{"name":"I.A.P.N.O.R. International Academy of Posture and Neuromyofascial Occlusion Research, Viale Gino Moretti 37, 63074 San Benedetto del Tronto (AP), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry C.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Division of Translational Oral Biology, School of Dental Medicine, State University of New York, Stony Brook, New York, NY 14214, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9550-2155","authenticated-orcid":true,"given":"Eleonora","family":"Ortu","sequence":"additional","affiliation":[{"name":"University of L\u2019Aquila, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, Building Delta 6\u2013Unit of Dentistry, V.le San Salvatore, L\u2019Aquila 67100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"9","key":"1","first-page":"627","volume":"18","year":"1984","journal-title":"Journal of Clinical Orthodontics: JCO"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2006.0036"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122826"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2011.08.004"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1179\/crn.2008.015"},{"issue":"4","key":"6","first-page":"343","volume":"58","year":"1988","journal-title":"Angle Orthodontist"},{"key":"7","year":"2007"},{"issue":"3","key":"8","first-page":"209","volume":"13","year":"2012","journal-title":"European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.08.008"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.2174\/1874210601408010020"},{"issue":"7","key":"11","first-page":"1632","volume":"7","year":"2014","journal-title":"International Journal of Clinical and Experimental Medicine"},{"issue":"12","key":"12","first-page":"8","volume":"12","year":"2018","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"13","year":"2007"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2015.04.003"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02090.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1151"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1017\/s0033291700009934"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2001.00030.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2005.01442.x"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/s1050-6411(98)00033-9"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/s1388-2457(01)00708-8"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-002-0661-x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045424"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1177\/0394632015572072"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2017.02.014"},{"issue":"2","key":"26","first-page":"129","volume":"37","year":"2019","journal-title":"Cranio-Journal of Craniomandibular Practice"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1080\/08869634.2018.1526849"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1996.0095"},{"issue":"2","key":"29","first-page":"104","volume":"36","year":"2002","journal-title":"Journal of Clinical Orthodontics: JCO"},{"key":"30","year":"1998"},{"key":"31","year":"2016"},{"key":"32","year":"2007"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-14-168"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2011.12.008"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1179\/0886963413z.00000000018"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2007.01769.x"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5957076"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1179\/crn.2005.029"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2011.11.040"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-014-0734-8"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1080\/08869634.2000.11746131"},{"issue":"pt 3","key":"42","first-page":"523","volume":"128","year":"1979","journal-title":"Journal of Anatomy"},{"issue":"4","key":"43","first-page":"288","volume":"108","year":"2017","journal-title":"La Medicina del Lavoro"},{"issue":"6","key":"44","doi-asserted-by":"crossref","first-page":"490","DOI":"10.14639\/0392-100X-1361","volume":"36","year":"2016","journal-title":"Acta Otorhinolaryngologica Italica: Organo Ufficiale Della Societa Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1016\/s0003-9969(99)00057-6"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1177\/154411130201300505"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.2174\/1874210601610010460"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(81)91127-6"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(77)90069-3"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1177\/00220345000790081701"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12048"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1068\/i0697sas"},{"issue":"1","key":"53","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF03321594","volume":"9","year":"2008","journal-title":"European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2008.10.007"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1067\/mpr.2001.115399"},{"issue":"6","key":"56","first-page":"450","volume":"131","year":"2014","journal-title":"Texas Dental Journal"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2013.0220"}],"updated-by":[{"DOI":"10.1155\/2020\/9465080","type":"corrigendum","label":"Corrigendum","source":"publisher","updated":{"date-parts":[[2020,4,18]],"date-time":"2020-04-18T00:00:00Z","timestamp":1587168000000}}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2019\/5646143.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2019\/5646143.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2019\/5646143.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T10:03:32Z","timestamp":1663409012000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/prm\/2019\/5646143\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,6]]},"references-count":57,"alternative-id":["5646143","5646143"],"URL":"https:\/\/doi.org\/10.1155\/2019\/5646143","relation":{},"ISSN":["1203-6765","1918-1523"],"issn-type":[{"value":"1203-6765","type":"print"},{"value":"1918-1523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,6]]}}}