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MSC-CM was collected and mixed with chitosan, collagen, and\n                    <jats:italic>\u03b2<\/jats:italic>\n                    -GP to generate the thermosensitive MSC-CM\/hydrogel, which was stored in the liquid phase at 4\u00b0C. The wounds of established third-degree burned mice were then externally covered with the MSC-CM\/hydrogel, which formed a gel when placed on the wounds at physiological temperature. Injured mice in three additional groups were treated with unconditioned MSC medium (UM), MSC-CM, or UM\/chitosan\/collagen\/\n                    <jats:italic>\u03b2<\/jats:italic>\n                    -GP thermosensitive hydrogels. Skin wound samples were obtained 4, 14, and 28 days after burning for further analysis by hematoxylin and eosin and Ki-67 staining. Wound healing rates and times, in addition to immunohistochemical results, were then compared and analyzed among the four groups. Application of the MSC-CM\/hydrogel shortened healing time, limited the area of inflammation, enhanced reepithelialization, promoted the formation of high-quality, well-vascularized granulation tissue, and attenuated the formation of fibrotic and hypertrophic scar tissue. In summary, MSC-CM\/hydrogel effectively promotes wound healing in third-degree burned mice.\n                  <\/jats:p>","DOI":"10.1155\/2019\/5768285","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T18:34:35Z","timestamp":1575311675000},"page":"1-14","source":"Crossref","is-referenced-by-count":47,"title":["A Human Umbilical Cord Mesenchymal Stem Cell-Conditioned Medium\/Chitosan\/Collagen\/\n                    <i>\u03b2<\/i>\n                    -Glycerophosphate Thermosensitive Hydrogel Promotes Burn Injury Healing in Mice"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1019-6436","authenticated-orcid":true,"given":"Panpan","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Qilu Hospital of Shandong University, Jinan 250012, 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