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Focus is placed on the mass spectrometric determination of the analytes along with the estimation of total polyphenolic and total flavonoid contents in the 70% ethanol extract. After partitioning the 70% ethanol extract in hexane, chloroform, ethyl acetate, <jats:italic>n<\/jats:italic>-butanol, and water, all the extracts were evaluated for their antioxidant, antidiabetic, and antimicrobial activities. The results delivered total polyphenolic compounds as gallic acid equivalents (1% w\/w) of the dried extract and total flavonoid contents as quercetin equivalents (0.2% w\/w) of the dried extract. Mass spectrometric analysis resulted in the identification of 15 compounds containing various derivatives of (epi)catechin, chlorogenic acid, kaempferol, isorhamnetin and their glycosides, ursolic acid, amygdalactone, and benzoic acid derivatives. Antioxidant activity experiments showed that highest activity was found in <jats:italic>n<\/jats:italic>-butanol extract among the studied samples with IC<jats:sub>50<\/jats:sub> value as 76.04\u2009<jats:italic>\u03bc<\/jats:italic>g\/ml, while hexane and chloroform extracts were active against the PTP1B enzyme with IC<jats:sub>50<\/jats:sub> values 9.66\u2009<jats:italic>\u03bc<\/jats:italic>g\/ml and 37.95\u2009<jats:italic>\u03bc<\/jats:italic>g\/ml, respectively. Hexane and chloroform fractions were active against <jats:italic>Staphylococcus aureus<\/jats:italic> with the zone of inhibition diameter 9\u2009mm and 12\u2009mm, respectively.<\/jats:p>","DOI":"10.1155\/2019\/5861692","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T18:31:23Z","timestamp":1574447483000},"page":"1-7","source":"Crossref","is-referenced-by-count":12,"title":["Chemical and Pharmacological Evaluation of Hulls of <i>Prunus dulcis<\/i> Nuts"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6436-6595","authenticated-orcid":true,"given":"Muhammad Nasimullah","family":"Qureshi","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Swabi, Anbar, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sodik","family":"Numonov","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China"},{"name":"Research Institution \u201cChinese-Tajik Innovation Center for Natural Products\u201d, Ayni St. 299\/2, Dushanbe 734063, Tajikistan"},{"name":"Center for Research in Innovative Technologies, Academy of Sciences of the Republic of Tajikistan, Ayni St. 299\/3, Dushanbe 734063, Tajikistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4652-6879","authenticated-orcid":true,"given":"Haji Akber","family":"Aisa","sequence":"additional","affiliation":[{"name":"Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China"},{"name":"Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0721996"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1021\/jf052812q"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jams.2015.1010.1001"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.4172\/2329-6836.1000131"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1021\/jf020660i"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1021\/jf0110194"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1021\/jf020661a"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1021\/jf60232a067"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1021\/jf60228a025"},{"issue":"4","key":"10","first-page":"865","volume":"27","year":"2014","journal-title":"Pakistan Journal of Pharmaceutical Sciences"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.3390\/molecules200611257"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/503139"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.3390\/molecules18010951"},{"key":"14","first-page":"11","volume":"3","year":"2012","journal-title":"Medicinal Plant"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2015.08.076"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.3390\/molecules17055030"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1107\/s1600536813017935"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.07.065"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2011.05.112"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2004.02.007"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/s0040-4039(02)00327-1"}],"container-title":["International Journal of Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijac\/2019\/5861692.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijac\/2019\/5861692.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijac\/2019\/5861692.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T18:31:26Z","timestamp":1574447486000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ijac\/2019\/5861692\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,22]]},"references-count":21,"alternative-id":["5861692","5861692"],"URL":"https:\/\/doi.org\/10.1155\/2019\/5861692","relation":{},"ISSN":["1687-8760","1687-8779"],"issn-type":[{"value":"1687-8760","type":"print"},{"value":"1687-8779","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,22]]}}}