{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:44:16Z","timestamp":1762476256426,"version":"build-2065373602"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T00:00:00Z","timestamp":1550707200000},"content-version":"vor","delay-in-days":51,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Surgery"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . Gastrointestinal stromal tumor (GIST) is an uncommon tumor of the GI tract usually seen in elderly patients, often difficult to diagnose because of the unspecific symptoms such as abdominal pain and fullness. Recurrent GIST may have an even more obscure clinical presentation.\n                    <jats:italic>Case Report<\/jats:italic>\n                    . A 44\u2010year\u2010old female with a history of surgically treated GIST presented to the emergency room complaining of acute onset sharp RLQ pain, nausea, and vomiting. Clinically, she had RLQ tenderness with rebound, her WBC was elevated, and CT scan showed signs of appendicitis and also soft tissue masses suspicious for malignancy. After contemplating treatment options including antibiotics and further workup, it was recommended to proceed with surgery. Laparoscopy showed a thickened appendix with nodular infiltration and multiple mass\u2010like lesions in the RLQ not amendable to minimal invasive resection. From a lower midline incision, an open appendectomy and excision of multiple masses in the terminal ileum and in the abdominal wall were done. Narrow\u2010based Meckel\u2019s diverticulum with multiple nodular lesions was also removed. Pathology identified appendicitis and serosal involvement of GIST in all specimens staining positive for CD68, CD117, and vimentin. The patient was started on imatinib and remained recurrence\u2010free after 6 months.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . This case illustrates a rare presentation of acute symptomatic recurrent metastatic GIST. Our patient was unusually young, and GIST recurrence presented with acute RLQ pain suggestive for acute appendicitis and also involved Meckel\u2019s diverticulum. Surgical debulking followed by imatinib seems to be a reasonable approach in such cases.\n                  <\/jats:p>","DOI":"10.1155\/2019\/6091515","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T18:34:29Z","timestamp":1550774069000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute Right Lower Abdomen in a Patient with a History of Gastrointestinal Stromal Tumor"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4787-9732","authenticated-orcid":false,"given":"Dabanjan","family":"Bandyopadhyay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8591-4308","authenticated-orcid":false,"given":"Hugo J. R.","family":"Bonatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,21]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004280000338"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2007.12.016"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2013.15.85.2430"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.21037\/tgh.2018.01.01"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2014.937707"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/030089161009600303"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.11.011"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2017.10.007"},{"key":"e_1_2_6_9_2","first-page":"121","article-title":"Meckel diverticulum harboring a rare gastrointestinal stromal tumor","volume":"17","author":"Berry A. C.","year":"2017","journal-title":"The Ochsner Journal"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/ases.12016"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S5634"},{"key":"e_1_2_6_12_2","first-page":"635","article-title":"Characteristics of emergency gastrointestinal stromal tumor (GIST)","volume":"62","author":"Ucar A. D.","year":"2015","journal-title":"Hepatogastroenterology"}],"container-title":["Case Reports in Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2019\/6091515.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2019\/6091515.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2019\/6091515","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:39:40Z","timestamp":1762475980000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2019\/6091515"}},"subtitle":[],"editor":[{"given":"Alexander R.","family":"Novotny","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1155\/2019\/6091515"],"URL":"https:\/\/doi.org\/10.1155\/2019\/6091515","archive":["Portico"],"relation":{},"ISSN":["2090-6900","2090-6919"],"issn-type":[{"type":"print","value":"2090-6900"},{"type":"electronic","value":"2090-6919"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"2018-07-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"6091515"}}