{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T21:29:37Z","timestamp":1788557377823,"version":"build-2803163510"},"reference-count":317,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T00:00:00Z","timestamp":1554595200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001111","name":"Cancer Australia","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100001111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001111","name":"Cancer Australia","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100001111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001111","name":"Cancer Australia","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100001111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001111","name":"Cancer Australia","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100001111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001111","name":"Cancer Australia","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100001111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001184","name":"Cure Cancer Australia Foundation","doi-asserted-by":"publisher","award":["APP1074033"],"award-info":[{"award-number":["APP1074033"]}],"id":[{"id":"10.13039\/501100001184","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001184","name":"Cure Cancer Australia Foundation","doi-asserted-by":"publisher","award":["APP1062607"],"award-info":[{"award-number":["APP1062607"]}],"id":[{"id":"10.13039\/501100001184","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001184","name":"Cure Cancer Australia Foundation","doi-asserted-by":"publisher","award":["APP1128152"],"award-info":[{"award-number":["APP1128152"]}],"id":[{"id":"10.13039\/501100001184","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001184","name":"Cure Cancer Australia Foundation","doi-asserted-by":"publisher","award":["APP1048972"],"award-info":[{"award-number":["APP1048972"]}],"id":[{"id":"10.13039\/501100001184","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001184","name":"Cure Cancer Australia Foundation","doi-asserted-by":"publisher","award":["MDA417129"],"award-info":[{"award-number":["MDA417129"]}],"id":[{"id":"10.13039\/501100001184","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2019,4,7]]},"abstract":"<jats:p>The mitochondrion is an essential organelle important for the generation of ATP for cellular function. This is especially critical for cells with high energy demands, such as neurons for signal transmission and cardiomyocytes for the continuous mechanical work of the heart. However, deleterious reactive oxygen species are generated as a result of mitochondrial electron transport, requiring a rigorous activation of antioxidative defense in order to maintain homeostatic mitochondrial function. Indeed, recent studies have demonstrated that the dysregulation of antioxidant response leads to mitochondrial dysfunction in human degenerative diseases affecting the nervous system and the heart. In this review, we outline and discuss the mitochondrial and oxidative stress factors causing degenerative diseases, such as Alzheimer\u2019s disease, Parkinson\u2019s disease, amyotrophic lateral sclerosis, Huntington\u2019s disease, and Friedreich\u2019s ataxia. In particular, the pathological involvement of mitochondrial dysfunction in relation to oxidative stress, energy metabolism, mitochondrial dynamics, and cell death will be explored. Understanding the pathology and the development of these diseases has highlighted novel regulators in the homeostatic maintenance of mitochondria. Importantly, this offers potential therapeutic targets in the development of future treatments for these degenerative diseases.<\/jats:p>","DOI":"10.1155\/2019\/6392763","type":"journal-article","created":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T23:31:12Z","timestamp":1554679872000},"page":"1-26","source":"Crossref","is-referenced-by-count":113,"title":["The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0693-7833","authenticated-orcid":true,"given":"Michael L.-H.","family":"Huang","sequence":"first","affiliation":[{"name":"Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building (K25), University of Sydney, Sydney, New South Wales 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5043-9586","authenticated-orcid":true,"given":"Shannon","family":"Chiang","sequence":"additional","affiliation":[{"name":"Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building (K25), University of Sydney, Sydney, New South Wales 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danuta S.","family":"Kalinowski","sequence":"additional","affiliation":[{"name":"Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building (K25), University of Sydney, Sydney, New South Wales 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Hun","family":"Bae","sequence":"additional","affiliation":[{"name":"Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building (K25), University of Sydney, Sydney, New South Wales 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Sahni","sequence":"additional","affiliation":[{"name":"Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building (K25), University of Sydney, Sydney, New South Wales 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0960-6415","authenticated-orcid":true,"given":"Des R.","family":"Richardson","sequence":"additional","affiliation":[{"name":"Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, Medical Foundation Building (K25), University of Sydney, Sydney, New South Wales 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-10-3856"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.12.022"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1038\/nature05292"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.114.300559"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/35041687"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.2016.1251711"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/emm.2014.122"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2017.02.001"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2728(98)00161-3"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2006.03.003"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/ng1292-324"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)05225-3"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201106-1152OC"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000338597.71702.ad"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1997.6943"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M003531200"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2015.06.021"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00180-12"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2012.388"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1096\/fj.10-171553"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M611336200"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1121572109"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.118976"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00248-10"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2021"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2013.08.003"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.03318"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1242\/bio.20134853"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.203216"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2008.02.014"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M606539200"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1007\/s11626-016-0105-2"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/b978-0-12-394625-6.00004-0"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1515\/hsz-2015-0295"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.05.017"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-005-0002-3"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/210934"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.258723"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1126\/science.1219855"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2005.06.014"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0407043101"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2007.1934"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.12.8.2245"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1089\/rej.2005.8.3"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2014.03.004"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200809125"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1126\/science.1096284"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201007013"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1038\/nature14893"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.120080"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201489847"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0913485107"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2017.12.008"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2014.75"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2009.256"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2422"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05722-3"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2007.04.004"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-180852"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1002\/em.20564"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.1774"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201801417r"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1021\/bi301721g"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80434-1"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1038\/34112"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-007-0718-8"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-8831-5_13"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2008.9"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2018.10.007"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.241655498"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.7A7273.2007"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(01)03206-9"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(03)01464-9"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1038\/nsb836"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00214"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1016\/j.artere.2017.12.002"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00331.2017"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4157(96)00014-7"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1038\/nature04512"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111789200"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M307847200"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2010.08.001"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R111.326876"},{"key":"84","doi-asserted-by":"publisher","DOI":"10.1007\/s10534-012-9529-7"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-01-068148"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0904519106"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.282517"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2007.1511"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200207030"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(02)00735-0"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M404500200"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1126\/science.1091230"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1868"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.4.918"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0403649101"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2012.742518"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.09.134"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2017.10.010"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1159\/000334901"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804871105"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr139"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddw330"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2385-16.2017"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-170051"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300410"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270502"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-018-1903-2"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1986.tb38398.x"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.07.004"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.06316.x"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2011.01.007"},{"key":"113","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1074-10.2010"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-016-0261-z"},{"key":"115","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2016.12.013"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00604-9"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/2856063"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.1515\/revneuro-2017-0063"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2011-111172"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21730"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.18.9866"},{"key":"122","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.13425"},{"key":"123","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-135749"},{"key":"124","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.490310111"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1186\/2051-5960-1-55"},{"key":"126","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207435200"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.06.011"},{"key":"128","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4285"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1020357"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70471-9"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-017-1686-y"},{"key":"132","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90291-2"},{"key":"133","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92366-0"},{"key":"134","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1990.tb05809.x"},{"key":"135","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24571"},{"key":"136","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2018.09.003"},{"key":"137","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(95)90302-X"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-150642"},{"key":"139","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-003-1302-y"},{"key":"140","doi-asserted-by":"publisher","DOI":"10.1038\/nm0602-600"},{"key":"141","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4641"},{"key":"142","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-28661-9.00005-6"},{"key":"143","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e3282f03db4"},{"key":"144","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2015.166"},{"key":"145","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M710012200"},{"key":"146","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4886(03)00342-X"},{"key":"147","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409713102"},{"key":"148","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2005.08.018"},{"key":"149","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaf3634"},{"key":"150","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.641746"},{"key":"151","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-017-1704-z"},{"key":"152","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2507-13.2014"},{"key":"153","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1659-16.2016"},{"key":"154","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04422-2"},{"key":"155","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2010.223"},{"key":"156","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0089-14.2015"},{"key":"157","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2017.01.002"},{"key":"158","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.06.143"},{"key":"159","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.11.036"},{"key":"160","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1713849115"},{"key":"161","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000298"},{"key":"162","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M505143200"},{"key":"163","doi-asserted-by":"publisher","DOI":"10.4238\/2012.May.21.6"},{"key":"164","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2017.427"},{"key":"165","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.04.032"},{"key":"166","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu520"},{"key":"167","doi-asserted-by":"publisher","DOI":"10.1126\/science.1077209"},{"key":"168","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703219104"},{"key":"169","doi-asserted-by":"publisher","DOI":"10.1038\/nature09536"},{"key":"170","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0032629"},{"key":"171","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2005.03145.x"},{"key":"172","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.307"},{"key":"173","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi007"},{"key":"174","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl104"},{"key":"175","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq430"},{"key":"176","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009367"},{"key":"177","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq288"},{"key":"178","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402959101"},{"key":"179","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607260103"},{"key":"180","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2006.07.019"},{"key":"181","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0813361106"},{"key":"182","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2010.3731"},{"key":"183","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-11-36"},{"key":"184","doi-asserted-by":"publisher","DOI":"10.1042\/BST20150003"},{"key":"185","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.10.023"},{"key":"186","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.11.005"},{"key":"187","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2013.10.013"},{"key":"188","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003985"},{"key":"189","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-014-8893-4"},{"key":"190","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2006.04.001"},{"key":"191","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddx320"},{"key":"192","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507360102"},{"key":"193","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/dds003"},{"key":"194","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt600"},{"key":"195","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi439"},{"key":"196","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.22.9848-9862.2004"},{"key":"197","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi215"},{"key":"198","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20713"},{"key":"199","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-009-9255-1"},{"key":"200","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-017-0196-0"},{"key":"201","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2018.6595"},{"key":"202","doi-asserted-by":"publisher","DOI":"10.1177\/1470320316672349"},{"key":"203","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61156-7"},{"key":"204","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2017.06.052"},{"key":"205","doi-asserted-by":"publisher","DOI":"10.1038\/362059a0"},{"key":"206","doi-asserted-by":"publisher","DOI":"10.1097\/nen.0b013e31802c396b"},{"key":"207","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt528"},{"key":"208","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt319"},{"key":"209","doi-asserted-by":"publisher","DOI":"10.1002\/stem.2388"},{"key":"210","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-016-0316-5"},{"key":"211","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq383"},{"key":"212","doi-asserted-by":"publisher","DOI":"10.2174\/15672026113109990060"},{"key":"213","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1630-10.2010"},{"key":"214","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.515940"},{"key":"215","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022031"},{"key":"216","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm226"},{"key":"217","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-4-16"},{"issue":"4","key":"218","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s004010100399","volume":"102","year":"2001","journal-title":"Acta Neuropathologica"},{"key":"219","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.06.016"},{"key":"220","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.07.019"},{"key":"221","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.06.021"},{"key":"222","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq202"},{"key":"223","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5385-12.2013"},{"key":"224","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33964-0"},{"key":"225","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4130"},{"key":"226","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu138"},{"key":"227","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201505496"},{"key":"228","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.11.018"},{"key":"229","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60111-1"},{"key":"230","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.5"},{"key":"231","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390317"},{"key":"232","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M504749200"},{"key":"233","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.15.7105"},{"key":"234","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1993.tb03634.x"},{"key":"235","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(93)90117-5"},{"key":"236","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-07-0607"},{"key":"237","doi-asserted-by":"publisher","DOI":"10.1038\/nn884"},{"key":"238","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh162"},{"key":"239","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-2772(03)00059-8"},{"key":"240","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(01)00213-1"},{"key":"241","doi-asserted-by":"publisher","DOI":"10.1126\/science.1092734"},{"key":"242","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.06.005"},{"key":"243","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2012.06.008"},{"key":"244","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.09.015"},{"key":"245","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2006.10.004"},{"key":"246","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.09.013"},{"key":"247","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.201000102"},{"key":"248","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2313"},{"key":"249","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05629.x"},{"key":"250","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq306"},{"key":"251","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr024"},{"key":"252","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr475"},{"key":"253","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1870-13.2014"},{"key":"254","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.581"},{"key":"255","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3101"},{"key":"256","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1420103111"},{"key":"257","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2006.8.2061"},{"key":"258","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2008.05.014"},{"key":"259","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408487101"},{"key":"260","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057932"},{"key":"261","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1308"},{"key":"262","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1614943114"},{"key":"263","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2010.03.017"},{"key":"264","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5254.1423"},{"key":"265","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(03)00004-3"},{"key":"266","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M101879200"},{"key":"267","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.11.1771"},{"key":"268","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610173351601"},{"key":"269","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.01.010"},{"key":"270","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906784106"},{"key":"271","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2017.08.021"},{"key":"272","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804261105"},{"key":"273","doi-asserted-by":"publisher","DOI":"10.1016\/S1357-2725(00)00067-4"},{"key":"274","doi-asserted-by":"publisher","DOI":"10.1002\/biof.5520180219"},{"key":"275","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-12-065433"},{"key":"276","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100006260"},{"key":"277","doi-asserted-by":"publisher","DOI":"10.1042\/CS20160072"},{"key":"278","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1215349109"},{"key":"279","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr187"},{"key":"280","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2013.05.032"},{"key":"281","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2018.11.020"},{"key":"282","doi-asserted-by":"publisher","DOI":"10.3390\/ijms160920704"},{"key":"283","doi-asserted-by":"publisher","DOI":"10.1080\/14737175.2016.1205488"},{"key":"284","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2014.12.012"},{"key":"285","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-011112-140320"},{"key":"286","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00188"},{"key":"287","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2012.12.011"},{"key":"288","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.04.012"},{"key":"289","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12212"},{"key":"290","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2011.00937.x"},{"key":"291","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2012.00978.x"},{"key":"292","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12113"},{"key":"293","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12588"},{"key":"294","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142438"},{"key":"295","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-018-02711-2"},{"key":"296","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.03.018"},{"key":"297","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2012.01.006"},{"key":"298","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00431"},{"key":"299","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-016-9879-1"},{"key":"300","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5593"},{"key":"301","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2014.12.012"},{"key":"302","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2016.03.010"},{"key":"303","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00632"},{"key":"304","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.06.014"},{"key":"305","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2009.3018"},{"key":"306","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70167-4"},{"key":"307","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2004.09.015"},{"key":"308","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.21367"},{"key":"309","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912925107"},{"key":"310","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.3921"},{"key":"311","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2143(98)90180-9"},{"key":"312","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(01)00041-2"},{"key":"313","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4889(82)90043-X"},{"key":"314","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2143(99)90173-7"},{"key":"315","doi-asserted-by":"publisher","DOI":"10.1124\/mol.108.046847"},{"key":"316","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.8.12.2141"},{"key":"317","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-009-0589-x"},{"key":"318","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-016-0288-5"}],"container-title":["Oxidative Medicine and Cellular Longevity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2019\/6392763.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2019\/6392763.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2019\/6392763.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T17:47:43Z","timestamp":1607190463000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/omcl\/2019\/6392763\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,7]]},"references-count":317,"alternative-id":["6392763","6392763"],"URL":"https:\/\/doi.org\/10.1155\/2019\/6392763","relation":{},"ISSN":["1942-0900","1942-0994"],"issn-type":[{"value":"1942-0900","type":"print"},{"value":"1942-0994","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,7]]}}}