{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T16:09:23Z","timestamp":1785600563948,"version":"3.56.0"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Japanese Ministry of Health, Labor, and Welfare","award":["18K09102"],"award-info":[{"award-number":["18K09102"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2019,11,18]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic> To investigate factors with a significant relationship with the absence of musculoskeletal disease (MSD: osteoporosis, knee osteoarthritis (K-OA), and lumbar spondylosis (L-OA)) in elderly people \u226570 years old. <jats:italic>Methods.<\/jats:italic> The subjects were 279 people (134 males, 145 females, mean age: 75.2 years) who attended an annual health checkup and were prospectively included in the study. Osteoporosis was defined as %YAM \u226470%, K-OA as Kellgren\u2013Lawrence grade \u22652, and L-OA as osteophytes of Nathan class \u22653. Subjects were divided into those with (group D) and without (group N) any MSD. Clinical variables including locomotive syndrome (LS), frailty, sarcopenia, and QOL (SF-36) were compared between the groups. <jats:italic>Results<\/jats:italic>. There was no significant difference in age or gender between group N (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>54<\/mml:mn><\/mml:mrow><\/mml:math>) and group D (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>225<\/mml:mn><\/mml:mrow><\/mml:math>). Lower BMI and pain, including neuropathic pain; greater back muscle strength, physical ability, and balance with eyes closed; larger lumbar lordosis, sacral inclination, and lumbar ROM; and smaller spinal inclination were found in group N. The rates of LS and sarcopenia were significantly lower and QOL was significantly higher in group N. <jats:italic>Conclusions<\/jats:italic>. This study firstly revealed the significant musculoskeletal factors and geriatric syndromes related to an absence of MSD, which may form the basis of interventions to improve QOL in elderly people \u226570\u2009years old.<\/jats:p>","DOI":"10.1155\/2019\/7097652","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T18:32:37Z","timestamp":1574101957000},"page":"1-7","source":"Crossref","is-referenced-by-count":9,"title":["Musculoskeletal Factors and Geriatric Syndromes Related to the Absence of Musculoskeletal Degenerative Disease in Elderly People Aged over 70\u2009Years"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6951-8575","authenticated-orcid":true,"given":"Shiro","family":"Imagama","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1721-9626","authenticated-orcid":true,"given":"Kazuyoshi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taisuke","family":"Seki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Ishizuka","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Machino","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayoshi","family":"Morozumi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Kanbara","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadayuki","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Ishiguro","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiharu","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Kansai University of Welfare Sciences, 3-11-1 Asahigaoka, Kashiwara, Osaka 582-0026, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-017-0794-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2019.1601839"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.85B1.13389"},{"issue":"3","key":"4","first-page":"329","volume":"77","year":"2015","journal-title":"Nagoya Journal of Medical Science"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s007760200092"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-012-0770-2"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2018.1441675"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-010-1606-4"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-011-0052-1"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.4.494"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-196244020-00003"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/brs.0b013e3182254a18"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-014-3251-9"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000003073"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068013"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1186\/s12875-016-0486-z"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200012150-00008"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2019.1623364"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-013-0382-5"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2207-1"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2017.1285856"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2018.1514705"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-013-2721-9"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2005.02.003"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-011-0108-5"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-011-0160-1"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-007-1202-6"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-011-0193-5"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-012-0266-0"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.13129"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.11.025"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2017.1349058"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.18999%2Fnagjms.80.4.519"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2011.06.015"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2007.07.392"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-14-87"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.089748"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-017-2825-5"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-007-0398-9"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-013-0476-0"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.16.01594"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3163-5"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31823e15e2"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2019\/7097652.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2019\/7097652.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2019\/7097652.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T18:32:42Z","timestamp":1574101962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2019\/7097652\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,18]]},"references-count":44,"alternative-id":["7097652","7097652"],"URL":"https:\/\/doi.org\/10.1155\/2019\/7097652","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,18]]}}}