{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:43:58Z","timestamp":1762476238891,"version":"build-2065373602"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"vor","delay-in-days":160,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Surgery"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Germ cell tumors (GCTs) arise along the midline, in which 50\u201070% of extragonadal GCTs occur in the mediastinum. Malignant GCTs are more common in males, while benign GCTs occur equally in both males and females. This report presents a case of a giant primary mediastinal nonseminomatous GCT resected from a 35\u2010year\u2010old male who presented with dyspnoea and tightness in the chest. Thorough investigations including a chest MRI were done. It showed a 21 \u00d7 19 \u00d7 15\u2009cm tumor. Thus, surgical resection of the tumor through a midline sternotomy was done. Histopathological analysis diagnosed the tumor as a primary mediastinal teratocarcinoma with a sarcomatous component. Eighteen\u2010month follow\u2010up showed no tumor recurrence. Mediastinal teratocarcinoma is a rare and life\u2010threatening germ cell tumor. Studies recommend the use of chemotherapy prior to resection as an important step in its management. Close and regular follow\u2010up postsurgical resection is advised.<\/jats:p>","DOI":"10.1155\/2019\/7123241","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T19:31:32Z","timestamp":1560195092000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Giant Primary Mediastinal Teratocarcinoma in a Male Adult"],"prefix":"10.1155","volume":"2019","author":[{"given":"Muneera","family":"Al-Khalifa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Alsaad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Habib","family":"Al-Tareef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaid","family":"Arekat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9448-5867","authenticated-orcid":false,"given":"Abdulla","family":"Darwish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,10]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2012.0039"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.55418\/9781933477077"},{"volume-title":"Cancer: Principles and Practice of Oncology","year":"2001","author":"Devita V. 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