{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:11:33Z","timestamp":1773123093586,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,7,24]],"date-time":"2019-07-24T00:00:00Z","timestamp":1563926400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2019,7,24]]},"abstract":"<jats:p>Mushrooms produce a variety of bioactive compounds that are known to have a potential source of antioxidant and antimicrobial properties. Natural antioxidants can protect against free radicals without any side effects. The purpose of this study was to evaluate the antioxidant and antimicrobial activities of<jats:italic> Auricularia<\/jats:italic> and<jats:italic> Termitomyces<\/jats:italic> extracts. Specimens of<jats:italic> Auricularia<\/jats:italic> and<jats:italic> Termitomyces<\/jats:italic> spp. were collected from Kakamega National Reserve Forest in Kenya. Specimens were identified, extracted, and screened for their antioxidant and antimicrobial activities using stable free radical DPPH and colorimetric bioassay methods, respectively. The antimicrobial activity of the extracts was tested against<jats:italic> Escherichia coli, Klebsiella pneumoniae<\/jats:italic>,<jats:italic> Pseudomonas aeruginosa<\/jats:italic>,<jats:italic> Staphylococcus aureus, <\/jats:italic>MRSA,<jats:italic> Candida albicans<\/jats:italic>, and<jats:italic> Candida parapsilosis<\/jats:italic>. The maximum scavenging activity of hot water extract of<jats:italic> Auricularia<\/jats:italic> spp. was observed at 70.4% with the IC<jats:sub>50<\/jats:sub> value of 40\u2009<jats:italic>\u03bc<\/jats:italic>g\/mL. Of the three extracts of<jats:italic> Termitomyces<\/jats:italic> spp., 70% ethanol extract has shown the highest scavenging activity (63%) with the IC<jats:sub>50<\/jats:sub> value of 50\u2009<jats:italic>\u03bc<\/jats:italic>g\/mL. Chloroform and hot water extracts of<jats:italic> Auricularia<\/jats:italic> have shown statistically significantly different antifungal activities against<jats:italic> C. parapsilosis<\/jats:italic> (<jats:italic>df <\/jats:italic>= 2, F = 22.49,<jats:italic> p <\/jats:italic>\u2264 0.05). Of all the organisms,<jats:italic> S. aureus<\/jats:italic> was highly susceptible to 70% ethanol and hot water extracts of<jats:italic> Termitomyces<\/jats:italic> spp. with minimum inhibitory concentration values of 0.67\u00b10.29\u2009mg\/mL.<jats:italic> S. aureus<\/jats:italic> and<jats:italic> E. coli<\/jats:italic> were the most susceptible and resistant bacteria to the hot water extract, respectively. In conclusion, the extracts of<jats:italic> Auricularia<\/jats:italic> spp. and<jats:italic> Termitomyces<\/jats:italic> spp. have shown promising antimicrobial and antioxidant activities.<\/jats:p>","DOI":"10.1155\/2019\/7357048","type":"journal-article","created":{"date-parts":[[2019,7,24]],"date-time":"2019-07-24T19:31:05Z","timestamp":1563996665000},"page":"1-10","source":"Crossref","is-referenced-by-count":37,"title":["Investigation of Antioxidant and Antimicrobial Activities of Different Extracts of<i> Auricularia<\/i> and<i> Termitomyces<\/i> Species of Mushrooms"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2697-4818","authenticated-orcid":true,"given":"Gebreselema","family":"Gebreyohannes","sequence":"first","affiliation":[{"name":"Department of Biological and Chemical Engineering, Mekelle Institute of Technology, Mekelle University, Ethiopia"},{"name":"Molecular Biology and Biotechnology, Pan African University, Institute for Basic Sciences, Technology, and Innovation, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Nyerere","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Bii","sequence":"additional","affiliation":[{"name":"Center for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3602-1578","authenticated-orcid":true,"given":"Desta B.","family":"Sbhatu","sequence":"additional","affiliation":[{"name":"Department of Biological and Chemical Engineering, Mekelle Institute of Technology, Mekelle University, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3390\/md13063479"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1081\/FRI-200051893"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1718025"},{"key":"4","first-page":"1","volume":"2019","year":"2019","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"key":"5","first-page":"1","volume":"7","year":"2016","journal-title":"Frontiers in Microbiology"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2014.12.002"},{"issue":"3","key":"7","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1080\/11263504.2016.1186125","volume":"151","year":"2017","journal-title":"Plant Biosystems - An International Journal Dealing with all Aspects of Plant 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