{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T03:41:38Z","timestamp":1772595698124,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T00:00:00Z","timestamp":1576713600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shanghai Municipal Medical and Health Discipline Construction Projects","award":["2017ZZ02015"],"award-info":[{"award-number":["2017ZZ02015"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mediators of Inflammation"],"published-print":{"date-parts":[[2019,12,19]]},"abstract":"<jats:p>The association of residual myometrium thickness (RMT) and scar defect depth (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>D<\/mml:mi><\/mml:math>) with menstrual abnormalities and the effectiveness of vaginal repair remain to be determined in patients with cesarean section scar diverticulum (CSD). To assess the value of ultrasound to predict vaginal repair effectiveness. This was a retrospective study of patients with CSD treated with vaginal repair between 01\/2014 and 02\/2016 at Shanghai First Maternity and Infant Hospital (Tongji University). Transvaginal ultrasound was performed before and 3 months after surgical repair. RMT, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>D<\/mml:mi><\/mml:math>, scar defect length (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>L<\/mml:mi><\/mml:math>), and scar defect width (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>W<\/mml:mi><\/mml:math>) were measured. Width (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>W<\/mml:mi><\/mml:math>), <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>D<\/mml:mi><\/mml:math>, and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>L<\/mml:mi><\/mml:math> increased along the duration of menstrual period (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>). When the menstrual extension time was \u226515 days, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mfenced open=\"(\" close=\")\"><mml:mrow><mml:mtext>RMT<\/mml:mtext><mml:mo>+<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:mrow><\/mml:mfenced><\/mml:math> were smaller than in patients with period &lt;15 days (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>). <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\"><mml:mi>L<\/mml:mi><\/mml:math> was the most positively correlated ultrasonic parameter with menstrual prolongation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\"><mml:mi>r<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.492<\/mml:mn><\/mml:math>). <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M15\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mfenced open=\"(\" close=\")\"><mml:mrow><mml:mtext>RMT<\/mml:mtext><mml:mo>+<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:mrow><\/mml:mfenced><\/mml:math> were negatively correlated with prolonged menstruation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M16\"><mml:mi>r<\/mml:mi><mml:mo>=<\/mml:mo><mml:mo>\u2010<\/mml:mo><mml:mn>0.304<\/mml:mn><\/mml:math> and -0.305, respectively). <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M17\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M18\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mfenced open=\"(\" close=\")\"><mml:mrow><mml:mtext>RMT<\/mml:mtext><mml:mo>+<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:mrow><\/mml:mfenced><\/mml:math> were associated with the disappearance of CSD after vaginal repair (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M19\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>). The cutoff value of <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M20\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mfenced open=\"(\" close=\")\"><mml:mrow><mml:mtext>RMT<\/mml:mtext><mml:mo>+<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:mrow><\/mml:mfenced><\/mml:math> was 0.496, with sensitivity of 53.0% and specificity of 61.4%. <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M21\"><mml:mi>L<\/mml:mi><\/mml:math> of CSD is closely correlated with menstrual extension but has no relationship with the effectiveness of surgery. <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M22\"><mml:mtext>RMT<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:mfenced open=\"(\" close=\")\"><mml:mrow><mml:mtext>RMT<\/mml:mtext><mml:mo>+<\/mml:mo><mml:mi>D<\/mml:mi><\/mml:mrow><\/mml:mfenced><\/mml:math> is correlated with menstrual extension time \u226515 days and the effectiveness of vaginal repair.<\/jats:p>","DOI":"10.1155\/2019\/7415891","type":"journal-article","created":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T18:32:16Z","timestamp":1576780336000},"page":"1-8","source":"Crossref","is-referenced-by-count":8,"title":["Association of Menstrual Extension and Surgery Effectiveness with Ultrasound Parameters of Cesarean Section Scar Diverticulum in Patients Undergoing Transvaginal Uterine Diverticulum Repair"],"prefix":"10.1155","volume":"2019","author":[{"given":"Qing","family":"Yang","sequence":"first","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Ren","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Lv","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7190-9295","authenticated-orcid":true,"given":"Fenghua","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k55"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004660.pub3"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32386-9"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12835"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2013.03.008"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6405"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1002\/j.2205-0140.2011.tb00120.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10077"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7539"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2018.06.012"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.890642"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2011.577252"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.02.007"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-014-0365-3"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2012.03.012"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.gyobfe.2013.08.005"},{"issue":"10","key":"17","first-page":"728","volume":"49","year":"2014","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"issue":"8","key":"18","first-page":"530","volume":"82","year":"2014","journal-title":"Ginecolog\u00eda y Obstetricia de M\u00e9xico"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5200"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6395"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-018-1821-2"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7496"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0000000000000257"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2016.06.013"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2016.01.007"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13255"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2017.1324833"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.2174\/1389203717666160322145939"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2017.09.022"}],"container-title":["Mediators of Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/mi\/2019\/7415891.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/mi\/2019\/7415891.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/mi\/2019\/7415891.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,19]],"date-time":"2019-12-19T18:32:22Z","timestamp":1576780342000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/mi\/2019\/7415891\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,19]]},"references-count":29,"alternative-id":["7415891","7415891"],"URL":"https:\/\/doi.org\/10.1155\/2019\/7415891","relation":{},"ISSN":["0962-9351","1466-1861"],"issn-type":[{"value":"0962-9351","type":"print"},{"value":"1466-1861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,19]]}}}