{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:36:25Z","timestamp":1747190185944,"version":"3.40.5"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2019,7,25]]},"abstract":"<jats:p>Hamartomatous polyps of Peutz-Jeghers type are strongly associated with Peutz-Jeghers polyposis syndrome and are predominantly encountered in the small intestine. Sporadic cases are uncommonly reported. We report a case of a polyp identified incidentally in the appendix of a patient undergoing diagnostic imaging due to a history of hepatitis C infection. Histopathologic evaluation after appendectomy showed a polyp with bands of muscularis mucosae bundles with arborizing architecture and variable amounts of inspissated mucin, morphologically indistinguishable from Peutz-Jeghers type hamartomatous polyp. A family or personal history of abdominal cancers was not reported by the patient, suggesting a sporadic occurrence. Next generation sequencing revealed only two pathogenic low-level<jats:italic> STK11<\/jats:italic> mutations, presumed to be somatic. In conclusion, this is an unusual case of a sporadic Peutz-Jeghers type polyp occurring in the appendix.<\/jats:p>","DOI":"10.1155\/2019\/7584070","type":"journal-article","created":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T19:32:41Z","timestamp":1564083161000},"page":"1-4","source":"Crossref","is-referenced-by-count":3,"title":["Peutz-Jeghers Type Polyp of the Appendix with Review of Literature"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9408-3139","authenticated-orcid":true,"given":"Jolanta","family":"Jedrzkiewicz","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Utah, 1950 Circle of Hope, Salt Lake City, UT 84112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith","family":"Quencer","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Utah, 1950 Circle of Hope, Salt Lake City, UT 84112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna P.","family":"Matynia","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Utah and ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT 84108, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen","family":"Morrow","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Utah, 50 N Medical Dr., Salt Lake City, UT 84132, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Pletneva","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Utah, 1950 Circle of Hope, Salt Lake City, UT 84112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonzalo","family":"Barraza","sequence":"additional","affiliation":[{"name":"George E. Wahlen Department of Veterans Affairs Medical Center, Department of Pathology, 500 Foothill Dr, Salt Lake City, UT 84148, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-005-2784-z"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.5402\/2011\/728579"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0219-9"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3180339944"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0411-x"},{"issue":"1","key":"6","first-page":"36","volume":"41","year":"2010","journal-title":"Korean J Gastrointest Endosc"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i16.4822"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/BF00311463"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-012-0190-0"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3919\/jjsa.73.2886"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235769"},{"issue":"11","key":"12","doi-asserted-by":"crossref","first-page":"347","DOI":"10.4251\/wjgo.v7.i11.347","volume":"7","year":"2015","journal-title":"World J Gastrointest Oncol"}],"container-title":["Case Reports in Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2019\/7584070.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2019\/7584070.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2019\/7584070.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T19:32:43Z","timestamp":1564083163000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cripa\/2019\/7584070\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,25]]},"references-count":12,"alternative-id":["7584070","7584070"],"URL":"https:\/\/doi.org\/10.1155\/2019\/7584070","relation":{},"ISSN":["2090-6781","2090-679X"],"issn-type":[{"type":"print","value":"2090-6781"},{"type":"electronic","value":"2090-679X"}],"subject":[],"published":{"date-parts":[[2019,7,25]]}}}