{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:47:41Z","timestamp":1790725661687,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T00:00:00Z","timestamp":1571184000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010014","name":"Six Talent Peaks Project in Jiangsu Province","doi-asserted-by":"publisher","award":["2014-WSN-025"],"award-info":[{"award-number":["2014-WSN-025"]}],"id":[{"id":"10.13039\/501100010014","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010014","name":"Six Talent Peaks Project in Jiangsu Province","doi-asserted-by":"publisher","award":["JDZX2015132"],"award-info":[{"award-number":["JDZX2015132"]}],"id":[{"id":"10.13039\/501100010014","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010014","name":"Six Talent Peaks Project in Jiangsu Province","doi-asserted-by":"publisher","award":["81370923"],"award-info":[{"award-number":["81370923"]}],"id":[{"id":"10.13039\/501100010014","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005891","name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","doi-asserted-by":"publisher","award":["2014-WSN-025"],"award-info":[{"award-number":["2014-WSN-025"]}],"id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005891","name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","doi-asserted-by":"publisher","award":["JDZX2015132"],"award-info":[{"award-number":["JDZX2015132"]}],"id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005891","name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","doi-asserted-by":"publisher","award":["81370923"],"award-info":[{"award-number":["81370923"]}],"id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2014-WSN-025"],"award-info":[{"award-number":["2014-WSN-025"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["JDZX2015132"],"award-info":[{"award-number":["JDZX2015132"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81370923"],"award-info":[{"award-number":["81370923"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2019,10,16]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To examine the effects of resistance training relative to aerobic training on abdominal adipose tissue and metabolic variables in adults with prediabetes. <jats:italic>Methods<\/jats:italic>. 105 participants with prediabetes were randomized into the resistance training group (RT, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>35<\/mml:mn><\/mml:math>), aerobic training group (AT, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>35<\/mml:mn><\/mml:math>), and control group (CG, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>35<\/mml:mn><\/mml:math>). The participants completed supervised 12-month exercise; the control group followed the primary lifestyle without exercise intervention. The primary outcomes were visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) measured by computed tomography (CT). Secondary outcomes were body composition, lipid profile, and metabolic variables. <jats:italic>Results<\/jats:italic>. A total of 93 participants completed the study. There were nonsignificant differences between groups before intervention. After training, VAT decreased significantly in AT and RT compared with CG (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.014<\/mml:mn><\/mml:math>, respectively). Although no significant difference in SAT was found across groups, SAT decreased significantly over time within each exercise group (all <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). Increase in muscle mass was greater in RT than that in AT and CG (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.031<\/mml:mn><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.045<\/mml:mn><\/mml:math>, respectively). Compared with CG, fasting plasma glucose (FPG) decreased significantly in RT and AT (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.003<\/mml:mn><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.014<\/mml:mn><\/mml:math>, respectively). There was a significant difference in the number of prediabetes who converted to diabetes among AT and RT, as compared with the control group (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.031<\/mml:mn><\/mml:math> and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.011<\/mml:mn><\/mml:math>, respectively). No significant differences were observed in lipid, waist-to-hip ratio (WHR), body mass index (BMI), fasting insulin (FI), 2-hour postprandial glucose (2hPG), glycosylated hemoglobin (HbA1c), HOMA-IR, and HOMA-<jats:italic>\u03b2<\/jats:italic> across groups. <jats:italic>Conclusion<\/jats:italic>. Both aerobic training and resistance training are effective in reducing abdominal adipose tissue and fasting plasma glucose in adults with prediabetes. Importantly, resistance training but not aerobic training is effective in augmenting muscle mass. <jats:italic>Trial Registration<\/jats:italic>. The trial is registered with <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02561377\">NCT02561377<\/jats:ext-link> (date of registration: 24\/09\/2015).<\/jats:p>","DOI":"10.1155\/2019\/8469739","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T19:30:55Z","timestamp":1571254255000},"page":"1-10","source":"Crossref","is-referenced-by-count":32,"title":["Effect of 12-Month Resistance Training on Changes in Abdominal Adipose Tissue and Metabolic Variables in Patients with Prediabetes: A Randomized Controlled Trial"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0185-7693","authenticated-orcid":true,"given":"Juan","family":"Yan","sequence":"first","affiliation":[{"name":"Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"},{"name":"Nursing College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2839-7698","authenticated-orcid":true,"given":"Xia","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2578-8407","authenticated-orcid":true,"given":"Jitao","family":"Feng","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5529-5705","authenticated-orcid":true,"given":"Xiaodan","family":"Yuan","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5892-9934","authenticated-orcid":true,"given":"Jianing","family":"Li","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3591-5262","authenticated-orcid":true,"given":"Lihong","family":"Yang","sequence":"additional","affiliation":[{"name":"Nursing College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7220-3697","authenticated-orcid":true,"given":"Panpan","family":"Zuo","sequence":"additional","affiliation":[{"name":"Nursing College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4181-2294","authenticated-orcid":true,"given":"Zhaohui","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Liu","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9547-3972","authenticated-orcid":true,"given":"Cunyi","family":"Hsue","sequence":"additional","affiliation":[{"name":"University of Massachusetts Amherst, Amherst, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junya","family":"Zhu","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua D.","family":"Miller","sequence":"additional","affiliation":[{"name":"Stony Brook University Hospital, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4743-0900","authenticated-orcid":true,"given":"Qingqing","family":"Lou","sequence":"additional","affiliation":[{"name":"Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.6.1475"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198812083192302"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012512"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-9920"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.983"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2337\/dc08-0109"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192521"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00033.2011"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1585"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.110320"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2011.00931.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2006.00250.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-s011"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2017.1364226"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1655"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.2337\/db12-0214"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.12.2335"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.4093\/kdj.2010.34.2.101"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s11897-011-0078-0"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-018-0755-3"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.3.662"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.20.4.537"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60766-7"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00285.2013"}],"container-title":["Journal of Diabetes Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2019\/8469739.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2019\/8469739.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2019\/8469739.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T19:30:57Z","timestamp":1571254257000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jdr\/2019\/8469739\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,16]]},"references-count":24,"alternative-id":["8469739","8469739"],"URL":"https:\/\/doi.org\/10.1155\/2019\/8469739","relation":{},"ISSN":["2314-6745","2314-6753"],"issn-type":[{"value":"2314-6745","type":"print"},{"value":"2314-6753","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,16]]}}}