{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:18:28Z","timestamp":1740140308049,"version":"3.37.3"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,2,24]],"date-time":"2019-02-24T00:00:00Z","timestamp":1550966400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2019,2,24]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. The aim of this study is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD.<jats:italic> Methods<\/jats:italic>. During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were recruited. The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two weeks after the ICD was recovered.<jats:italic> Results<\/jats:italic>. There were no significant differences in age and sex between ICD and control groups. It was found that skin median melanin value (176.50 vs 189.50,<jats:italic> P <\/jats:italic>&lt; 0.05, Mann-Whitney U-test) and erythema value (319.90 \u00b1 70.49 vs 347.93 \u00b1 84.55,<jats:italic> P <\/jats:italic>&lt; 0.05, Independent-Samples T test) were much lower in ICD than control group. Overall patch test results were not different, but the positivity rate of nickel sulfate (15.44% vs 4.00%,<jats:italic> P <\/jats:italic>&lt; 0.05, Fisher\u2019s exact test) was significantly higher in ICD group.<jats:italic> Conclusions<\/jats:italic>. In conclusion, people with nickel allergy, lower values of skin melanin, and erythema are predisposing to develop ICD.<\/jats:p>","DOI":"10.1155\/2019\/8612561","type":"journal-article","created":{"date-parts":[[2019,2,24]],"date-time":"2019-02-24T18:31:35Z","timestamp":1551033095000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8604-2425","authenticated-orcid":true,"given":"Hai-yan","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing 100050, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8736-6464","authenticated-orcid":true,"given":"Lin-feng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing 100050, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.3109\/13880209.2010.544043"},{"key":"2","first-page":"1586","volume":"49","year":"2007","journal-title":"Modern Journal of Integrated Traditional Chinese and Western Medicine"},{"key":"3","first-page":"115","volume":"18","year":"2011","journal-title":"Modern Medicine Journal of China"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.1016\/j.clindermatol.2013.05.033"},{"doi-asserted-by":"publisher","key":"5","DOI":"10.1111\/j.1600-0536.2010.01706.x"},{"doi-asserted-by":"publisher","key":"6","DOI":"10.1111\/j.1600-0536.2007.01182.x"},{"doi-asserted-by":"publisher","key":"7","DOI":"10.1093\/occmed\/kqv067"},{"doi-asserted-by":"publisher","key":"8","DOI":"10.1007\/3-540-31301-X"},{"doi-asserted-by":"publisher","key":"9","DOI":"10.1111\/j.1600-0536.2009.01507.x"},{"doi-asserted-by":"publisher","key":"10","DOI":"10.1067\/mjd.2003.220"},{"doi-asserted-by":"publisher","key":"11","DOI":"10.1097\/DER.0000000000000277"},{"issue":"11","key":"12","first-page":"1182","volume":"97","year":"2014","journal-title":"Journal of the Medical Association of Thailand"}],"container-title":["Evidence-Based Complementary and Alternative Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2019\/8612561.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2019\/8612561.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ecam\/2019\/8612561.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,24]],"date-time":"2019-02-24T18:31:36Z","timestamp":1551033096000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/ecam\/2019\/8612561\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,24]]},"references-count":12,"alternative-id":["8612561","8612561"],"URL":"https:\/\/doi.org\/10.1155\/2019\/8612561","relation":{},"ISSN":["1741-427X","1741-4288"],"issn-type":[{"type":"print","value":"1741-427X"},{"type":"electronic","value":"1741-4288"}],"subject":[],"published":{"date-parts":[[2019,2,24]]}}}