{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:33:06Z","timestamp":1791387186269,"version":"4.3.3"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:00:00Z","timestamp":1571875200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry Research International"],"published-print":{"date-parts":[[2019,10,24]]},"abstract":"<jats:p>The use of plant-based medicine is popular amongst individuals and communities in developing countries. <jats:italic>Duranta erecta<\/jats:italic> has been used in Africa and Asia to treat a wide range of diseases. This study evaluated the phytochemical profile and antioxidant and antimicrobial activities of <jats:italic>D. erecta<\/jats:italic> to ascertain its health benefits in traditional medicine. Phytochemical constituents and antimicrobial effect of the hydroethanolic extract of <jats:italic>D. erecta<\/jats:italic> leaves (DRL), unripe fruits (DRU), and ripe fruits (DRR) were investigated by standard methods. Elemental analyses were carried out by atomic absorption spectroscopy (AAS) on the raw sample and extract. FTIR and UV-VIS spectroscopy were used to identify functional groups. Extracts were screened for their possible antioxidant activities by three tests. The total phenolic and total tannin contents were evaluated by using the Folin\u2013Ciocalteu method. Total flavonoid content was determined by the aluminium chloride colorimetric assay method. The antioxidant activities were evaluated using the DPPH scavenging activity. The results of phytochemical screening showed the presence of triterpenoids, sterols, alkaloids, flavonoids, saponins, glycosides, and tannins. FTIR analysis revealed the presence of alcohols, phenols, alkanes, aldehydes, ketones, aromatics, aliphatic amines, aromatic amines, amides, carboxylic acids, esters, nitro compounds, alkynes, primary and secondary amines, and alkyl halides. Iron, zinc, and copper were also detected. Total phenolic and tannin contents ranged from 2.20\u2009\u00b1\u20090.15 to 14.54\u2009\u00b1\u20090.29\u2009mg gallic acid equivalent (GAE)\/100\u2009g and 3.55\u2009\u00b1\u20090.07 to 13.82\u2009\u00b1\u20090.04\u2009mg GAE\/100\u2009g, respectively. Total flavonoid content varied from 41.76\u2009\u00b1\u20090.96 to 343.49\u2009\u00b1\u20093.45\u2009<jats:italic>\u03bc<\/jats:italic>g quercetin equivalent (QE)\/100\u2009g. The highest DPPH scavenging activity was recorded in the methanolic fraction of the leaves. The antimicrobial assay of the extract or fractions recorded no activity against the test organisms. The outcome of this study affirmed that <jats:italic>D. erecta<\/jats:italic> contains phytochemicals and bioactive compounds that could be of health benefit.<\/jats:p>","DOI":"10.1155\/2019\/8731595","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T19:32:50Z","timestamp":1571945570000},"page":"1-11","source":"Crossref","is-referenced-by-count":39,"title":["Phytochemical, Antimicrobial, and Antioxidant Profiles of <i>Duranta erecta<\/i> L. Parts"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8019-2393","authenticated-orcid":true,"given":"Shadrack","family":"Donkor","sequence":"first","affiliation":[{"name":"Applied Radiation Biology Centre, Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, Legon, Accra, Ghana"},{"name":"Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4927-4419","authenticated-orcid":true,"given":"Christopher","family":"Larbie","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5041-117X","authenticated-orcid":true,"given":"Gustav","family":"Komlaga","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin Obukowho","family":"Emikpe","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, University of Ibadan, Ibadan, Nigeria"},{"name":"Department of Pathobiology, School of Veterinary Medicine, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, 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