{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T15:16:31Z","timestamp":1781795791518,"version":"3.54.5"},"reference-count":33,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008816","name":"University of Sri Jayewardenepura","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008816","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2019,7,9]]},"abstract":"<jats:p>Epidemiologic studies from South Asian countries have reported vitamin D deficiency among all age groups. However, there is very little information on vitamin D levels, especially in the vulnerable populations (pregnant\/breast feeding mother and infants) in Sri Lanka. More data on vitamin D status of such populations will be important for policy decisions to be made at a national level. Similarly, it will be valuable for healthcare programs in other countries (e.g., United States, Australia, Europe, and Canada) as Sri Lankans are a fast-growing migrant population to those countries. The purpose of this study was to investigate maternal vitamin D status and its effects on infants in a state sector tertiary care centre in Sri Lanka. This prospective cohort study was conducted on 140 healthy pregnant mothers in the third trimester (mean gestational age 39\u00b11 weeks). Blood was collected for 25(OH)D and parathyroid hormone (PTH). Sun exposure and feeding patterns of the infants were recorded based on maternal reporting. Mean age of the infants at follow-up visit was 36\u00b17 days. Vitamin D (25 (OH)D) deficiency (&lt;25 nmol\/L) was observed in 12% pregnant mothers, 5% lactating mothers, and 63% infants. Insufficiency (&lt;50 nmol\/L) was found in an additional 51% and 43% in pregnant and lactating mothers and 25% of infants. Mean 25(OH)D was higher in pregnant (46.4\u00b117.5 nmol\/L) and lactating (51.9\u00b117.0 nmol\/L) mothers than infants (28.1\u00b113.7 nmol\/L). Maternal vitamin D level during pregnancy was a significant risk factor (OR: 6.00, 95%CI: 1.522-23.655) for infant deficiency and insufficiency. Sun exposure of infants showed a significant positive correlation with vitamin D level (OR: 3.23, 95%CI: 1.19-8.68). In conclusion, the presence of Vitamin D deficiency\/insufficiency is higher in infants compared to pregnant\/lactating mothers. Low maternal 25(OH)D during pregnancy was a risk factor for deficiency in infants. Although majority of lactating mothers had sufficient vitamin D, most of their exclusively breastfed offspring were deficient.<\/jats:p>","DOI":"10.1155\/2019\/9017951","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T19:31:38Z","timestamp":1562700698000},"page":"1-6","source":"Crossref","is-referenced-by-count":15,"title":["Maternal Vitamin D Status and Its Effect on Vitamin D Levels in Early Infancy in a Tertiary Care Centre in Sri Lanka"],"prefix":"10.1155","volume":"2019","author":[{"given":"Kaneshapillai","family":"Anusha","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6616-222X","authenticated-orcid":true,"given":"Usha","family":"Hettiaratchi","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Medical Sciences, 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