{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:39:31Z","timestamp":1790753971651,"version":"4.1.0"},"reference-count":108,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T00:00:00Z","timestamp":1559520000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stem Cells International"],"published-print":{"date-parts":[[2019,6,3]]},"abstract":"<jats:p>Skeletal stem cells (SSCs) are postnatal self-renewing, multipotent, and skeletal lineage-committed progenitors that are capable of giving rise to cartilage, bone, and bone marrow stroma including marrow adipocytes and stromal cells in vitro and in an exogenous environment after transplantation in vivo. Identifying and isolating defined SSCs as well as illuminating their spatiotemporal properties contribute to our understating of skeletal biology and pathology. In this review, we revisit skeletal stem cells identified most recently and systematically discuss their origin and distributions.<\/jats:p>","DOI":"10.1155\/2019\/9026729","type":"journal-article","created":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T23:34:00Z","timestamp":1559604840000},"page":"1-11","source":"Crossref","is-referenced-by-count":6,"title":["New Insights on Properties and Spatial Distributions of Skeletal Stem Cells"],"prefix":"10.1155","volume":"2019","author":[{"given":"Jun-qi","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5493-1850","authenticated-orcid":true,"given":"Qi-wen","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1078-9116","authenticated-orcid":true,"given":"Zhen","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2014.03.003"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2016"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a031559"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2011.23"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/nature01660"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08657-9"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06075-5"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27833"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms12794"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201899398"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2017.01.001"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06898-4"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/boneres.2017.44"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-018-06756-9"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.03.002"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2018.11.007"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1242\/dev.102210"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3028"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.08.007"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1080\/14653240600855905"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2012.02.003"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2005.11.1198"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v034a14"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.07.029"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.12.002"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1007\/s40610-017-0075-5"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2009.238"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-100913-013132"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2018.041"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.09.006"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1038\/nature01657"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1210\/er.2002-0033"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a008334"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1172\/JCI11706"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2009.04.003"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1210\/endo.143.5.8776"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-0989-6"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.10.025"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1359\/JBMR.041013"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1321210110"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.5.1331"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2018.00127"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.06.040188.002121"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.12.034"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00283"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.08.025"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-1544"},{"issue":"8","key":"48","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1182\/blood.V92.8.2613","volume":"92","year":"1998","journal-title":"Blood"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5275.663"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0662-5"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.347716"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3139"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2013.12.013"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-018-0030-y"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02171-2"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1694"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1038\/ng1178"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.22730"},{"issue":"23","key":"59","doi-asserted-by":"crossref","first-page":"5515","DOI":"10.1242\/dev.126.23.5515","volume":"126","year":"1999","journal-title":"Development"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.11.042"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1038\/nature09262"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.06.008"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.12.093"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.07.003"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2003.18.4.696"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1038\/nature07547"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1038\/nature11926"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20122252"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/975871"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2006-0644"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-015-8470-2"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.02.009"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1038\/nature08099"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2017.05.013"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1734"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)01049-8"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1038\/32911"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.6.3511"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3570"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7098456"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.02.015"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2014.06.004"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.4252\/wjsc.v7.i3.583"},{"key":"84","doi-asserted-by":"publisher","DOI":"10.1242\/dev.023788"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1126\/science.1085672"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1242\/dev.096693"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2016.11.008"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3166"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2004.07.014"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2015-0013"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2140"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03124-z"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1172\/JCI64840"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3227"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3136"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1038\/nature12396"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0554-8"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1310212110"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2012.08.010"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20833"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.2174\/1574888X09666140213142258"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2005.00475.x"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1073>3.0.CO;2-F"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01786"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2006.10.018"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2000727"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3171"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10526"}],"container-title":["Stem Cells International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/sci\/2019\/9026729.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/sci\/2019\/9026729.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/sci\/2019\/9026729.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T06:58:18Z","timestamp":1663570698000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/sci\/2019\/9026729\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,3]]},"references-count":108,"alternative-id":["9026729","9026729"],"URL":"https:\/\/doi.org\/10.1155\/2019\/9026729","relation":{},"ISSN":["1687-966X","1687-9678"],"issn-type":[{"value":"1687-966X","type":"print"},{"value":"1687-9678","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,3]]}}}