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Some studies have shown that plant polysaccharides may have the ability to promote wound healing. The aim of this work was to evaluate the wound healing activity of the polysaccharide extracted from\n                    <jats:italic>Bletilla striata.<\/jats:italic>\n                    Firstly, a\n                    <jats:italic>Bletilla striata<\/jats:italic>\n                    polysaccharide was extracted by water extraction and alcohol precipitation and characterized by Fourier transform infrared spectroscopy. The\n                    <jats:italic>Bletilla striata<\/jats:italic>\n                    polysaccharide was then tested for cell migration and proliferation using the mouse fibroblast cell line. Then, the\n                    <jats:italic>Bletilla striata<\/jats:italic>\n                    hydrogel was fabricated for acute wound health care of the mouse full-thickness excision. The results showed that the BSP enhanced the proliferation and migration of L929 cells. The superior wound healing capacity of the BSP hydrogel was demonstrated that it significantly accelerated the wound healing process\n                    <jats:italic>in vivo<\/jats:italic>\n                    in full-thickness skin defect wounded models. Compared to the saline group, the BSP hydrogel could accelerate wound healing and promote re-epithelialization and collagen deposition by means of TGF-\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \/Smad signal pathway activation. Taken together, BSP hydrogel would be a useful pharmaceutic candidate for acute cutaneous wound health care.\n                  <\/jats:p>","DOI":"10.1155\/2019\/9212314","type":"journal-article","created":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T19:32:55Z","timestamp":1571945575000},"page":"1-9","source":"Crossref","is-referenced-by-count":43,"title":["Effect of Polysaccharides from\n                    <i>Bletilla striata<\/i>\n                    on the Healing of Dermal Wounds in Mice"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7543-3287","authenticated-orcid":true,"given":"Chen","family":"Zhang","sequence":"first","affiliation":[{"name":"Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"He","sequence":"additional","affiliation":[{"name":"Pharmacy College, Chengdu University of Traditional Chinese 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