{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T02:18:47Z","timestamp":1766197127244,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Interventional Cardiology"],"published-print":{"date-parts":[[2019,6,4]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. We sought to assess if ineligibility to coronary artery bypass grafting (CABG) constitutes a risk factor in patients who underwent a nonemergent unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with prophylactic Impella\u00ae heart pump support.<jats:italic> Background<\/jats:italic>. ULMCA PCI in patients not deemed eligible for CABG is associated with significantly worse outcomes compared to ULMCA PCI in eligible patients.<jats:italic> Methods<\/jats:italic>. Patients from the cVAD Registry and the PROTECT II trial who underwent a nonemergent ULMCA PCI were identified. We compared in-hospital mortality and major adverse cardiac and cerebrovascular event (MACCE) rates as well as 30-day survival and MACCE rates between CABG ineligible and CABG eligible patients.<jats:italic> Results<\/jats:italic>. A total of 331 patients were included (293 Impella 2.5\u00ae, 38 Impella CP\u00ae); 227 were ineligible for CABG and 104 were eligible. Baseline characteristics were remarkable for a trend toward higher rate of chronic obstructive pulmonary disease in the ineligible patients. In-hospital mortality (3.52% vs. 5.77%; p=0.383) and MACCE (6.61% vs. 7.69%; p=0.816) rates as well as 30-day survival (92.0% vs. 93.4%; Log-Rank p-value =0.781) and MACCE (88.1% vs. 90.1%; Log-Rank p-value=0.648) rates were not different between the two groups.<jats:italic> Conclusions<\/jats:italic>. The results of our study suggest that prophylactic Impella support appears to mitigate the risks inherent to surgical ineligibility in patients undergoing a nonemergent ULMCA PCI. Our results require further investigation.<\/jats:p>","DOI":"10.1155\/2019\/9691753","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T19:31:22Z","timestamp":1559676682000},"page":"1-9","source":"Crossref","is-referenced-by-count":6,"title":["Nonemergent Percutaneous Coronary Intervention on an Unprotected Left Main Coronary Artery Supported with Impella\u00ae Heart Pump in Patients Ineligible for Surgical Revascularization"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6350-4666","authenticated-orcid":true,"given":"Perwaiz M.","family":"Meraj","sequence":"first","affiliation":[{"name":"Northwell Health, Department of Cardiology, Manhasset, NY 11030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Dixon","sequence":"additional","affiliation":[{"name":"Beaumont Health, Department of Cardiovascular Medicine, Royal Oak, MI 48073, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffery","family":"Moses","sequence":"additional","affiliation":[{"name":"Columbia University Medical Center, New York, NY 10032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Technische Universit\u00e4t Dresden, Department of Internal Medicine and Cardiology, Dresden, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Hannover Medical Center, Department of Cardiology and Angiology, Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Akin","sequence":"additional","affiliation":[{"name":"Mannheim Medical School, Department of Cardiology and Angiology, Mannheim, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Hill","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital, London SE5 9RS, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore","family":"Schreiber","sequence":"additional","affiliation":[{"name":"Detroit Medical Center, Department of Cardiology, Detroit, MI 48201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William W.","family":"O\u2019Neill","sequence":"additional","affiliation":[{"name":"Henry Ford Medical Center, Department of Interventional Cardiology and Structural Heart, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32052-9"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1610227"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.06.051"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2017.03.022"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.2895"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.05.136"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.05.052"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.114.001846"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M09_01"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.07.017"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.098194"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.011541"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.06.010"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26781"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26979"}],"container-title":["Journal of Interventional Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jitc\/2019\/9691753.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jitc\/2019\/9691753.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jitc\/2019\/9691753.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T19:31:23Z","timestamp":1559676683000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jitc\/2019\/9691753\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,4]]},"references-count":15,"alternative-id":["9691753","9691753"],"URL":"https:\/\/doi.org\/10.1155\/2019\/9691753","relation":{},"ISSN":["0896-4327","1540-8183"],"issn-type":[{"type":"print","value":"0896-4327"},{"type":"electronic","value":"1540-8183"}],"subject":[],"published":{"date-parts":[[2019,6,4]]}}}