{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T08:51:53Z","timestamp":1744188713829,"version":"3.37.3"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T00:00:00Z","timestamp":1548028800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pulmonology"],"published-print":{"date-parts":[[2019,1,21]]},"abstract":"<jats:p>Lymphomatoid granulomatosis (LG) is an EBV-associated angiodestructive lymphoproliferative disease with multiorgan involvement that predominantly affects the lungs. We present a case of a 72-year-old man with a history of chronic lymphocytic leukemia who presented with upper respiratory symptoms and multiple erythematous skin papules. Chest CT showed ill-defined, irregular solid pulmonary nodules with peripheral ground-glass opacities in a peribronchovascular distribution. The differential for this pattern of lung disease is vast which includes but is not limited to infection, vasculitis, sarcoidosis, lymphoma, and Kaposi sarcoma. Subsequent PET\/CT showed rapid progression of lung opacities and marked FDG uptake of pulmonary opacities and skin nodules, which raised the question of Richter syndrome. Wedge biopsy under video-assisted thoracoscopic surgery was performed. Pathology showed an extensive lymphoid infiltrate involving lymphatic and bronchovascular bundles and consisting of a mixture of large lymphocytes and inflammatory cells. Special stains showed that the large lymphocytes expressed B-cell markers and EBV virus. Overall, the findings were consistent with LG.<\/jats:p>","DOI":"10.1155\/2019\/9870494","type":"journal-article","created":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T21:14:01Z","timestamp":1548105241000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["Lymphomatoid Granulomatosis in a Patient with Chronic Lymphocytic Leukemia and Rapidly Progressing Peribronchovascular Pulmonary Infiltrates"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4101-9528","authenticated-orcid":true,"given":"Shahab","family":"Rezvani","sequence":"first","affiliation":[{"name":"Beaumont Health, Oakland University William Beaumont School of Medicine, Department of Diagnostic Radiology and Molecular Imaging, 3601 W 13 Mile Rd, Royal Oak, MI 48073, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0279-5113","authenticated-orcid":true,"given":"Marie","family":"Tominna","sequence":"additional","affiliation":[{"name":"Beaumont Health, Oakland University William Beaumont School of Medicine, Department of Diagnostic Radiology and Molecular Imaging, 3601 W 13 Mile Rd, Royal Oak, MI 48073, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0761-661X","authenticated-orcid":true,"given":"Sayf","family":"Al-Katib","sequence":"additional","affiliation":[{"name":"Beaumont Health, Oakland University William Beaumont School of Medicine, Department of Diagnostic Radiology and Molecular Imaging, 3601 W 13 Mile Rd, Royal Oak, MI 48073, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc D.","family":"Smith","sequence":"additional","affiliation":[{"name":"Beaumont Health, Oakland University William Beaumont School of Medicine, Department of Clinical Pathology, 3601 W 13 Mile Rd, Royal Oak, MI 48073, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig","family":"Cousineau","sequence":"additional","affiliation":[{"name":"Beaumont Health, Oakland University William Beaumont School of Medicine, Department of Clinical Pathology, 3601 W 13 Mile Rd, Royal Oak, MI 48073, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayad","family":"Al-Katib","sequence":"additional","affiliation":[{"name":"Wayne State University School of Medicine, Lymphoma Research Laboratory, 540 E Canfield Room No. 8829, Detroit, MI 48202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-01-643569"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4084\/mjhid.2014.017"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(72)80005-4"},{"key":"4","first-page":"233","volume":"30","year":"1997","journal-title":"Cancer Surveys"},{"year":"2017","key":"5"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(79)80017-3"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.175.5.1751335"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2016140339"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820515)49:10<2070::AID-CNCR2820491019>3.0.CO;2-S"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.968"},{"year":"2006","key":"11"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1986.tb07575.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2007.06801.x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2012.710327"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131448"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31804bdaf8"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403249"}],"container-title":["Case Reports in Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripu\/2019\/9870494.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripu\/2019\/9870494.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripu\/2019\/9870494.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T21:14:03Z","timestamp":1548105243000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cripu\/2019\/9870494\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,21]]},"references-count":17,"alternative-id":["9870494","9870494"],"URL":"https:\/\/doi.org\/10.1155\/2019\/9870494","relation":{},"ISSN":["2090-6846","2090-6854"],"issn-type":[{"type":"print","value":"2090-6846"},{"type":"electronic","value":"2090-6854"}],"subject":[],"published":{"date-parts":[[2019,1,21]]}}}