{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T18:13:30Z","timestamp":1775499210305,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T00:00:00Z","timestamp":1586736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2020,4,13]]},"abstract":"<jats:p>We report a case of a 74-year-old man with a cluster of differentiation (CD) 7-positive diffuse large B-cell lymphoma (DLBCL) in the right nasal cavity. Flow cytometry analyses showed CD7 and CD20 positivity in tumor cells. The patient received 6 cycles of R-CHOP plus local radiation therapy because positron emission tomography-computed tomography after R-CHOP revealed an intranasal lesion. The patient achieved complete remission (CR) after radiation therapy. The frequency of CD7-positive DLBCL is rare, and only 11 cases with follow-up of clinical course have been reported thus far. CR or partial response was noted in 8 of 11 cases after receiving rituximab combined with chemotherapy. In total, 9 of 12 cases involved the development of extranodal lesions, which occurred as an intranasal tumor in 3 cases. It is important to examine the clinical features by accumulation of further cases.<\/jats:p>","DOI":"10.1155\/2020\/1514729","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T23:30:43Z","timestamp":1586820643000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["CD7-Positive Diffuse Large B-Cell Lymphoma Presenting as an Intranasal Tumor"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0339-0115","authenticated-orcid":true,"given":"Kazuaki","family":"Teshima","sequence":"first","affiliation":[{"name":"Department of Hematology, Hiraka General Hospital, Yokote, Japan"},{"name":"Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Kume","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hiraka General Hospital, Yokote, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Kawaharada","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiraka General Hospital, Yokote, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Hiraka General Hospital, Yokote, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ko","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hiraka General Hospital, Yokote, Japan"},{"name":"Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sho","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, 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Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Enomoto","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hiraka General Hospital, Yokote, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahito","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Hiraka General Hospital, Yokote, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satsuki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Hiraka General Hospital, Yokote, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology, Hiraka General Hospital, Yokote, 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