{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:36:53Z","timestamp":1747190213850,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Surgery"],"published-print":{"date-parts":[[2020,8,3]]},"abstract":"<jats:p>Laryngeal secondary malignancies are rare, and most spread locoregionally from hypopharyngeal or thyroid primaries. Metastasis of ovarian carcinoma to the larynx is extremely rare. A 65-year-old woman with a history of high grade serous ovarian carcinoma was undergoing carboplatin chemotherapy for recurrence. She presented with progressive dysphagia and hoarseness; a computer tomography (CT) scan demonstrated bilateral necrotic lymphadenopathy and hypopharyngeal fullness. A hypopharyngeal mass was confirmed on examination, and operative biopsy identified it as high-grade serous ovarian. To our knowledge, this report describes the second immunohistochemically proven metastatic ovarian cancer detected in the larynx in the world literature.<\/jats:p>","DOI":"10.1155\/2020\/1543129","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T23:31:57Z","timestamp":1596497517000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Ovarian Cancer Metastasis to the Larynx: A Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7072-4942","authenticated-orcid":true,"given":"Chad","family":"Purcell","sequence":"first","affiliation":[{"name":"Division of Otolaryngology-Head and Neck Surgery, Dalhousie University, QEII Health Sciences Centre, 3rd Floor Dickson Building, 5820 University Avenue, Halifax, Nova Scotia, Canada B3H 1Y9"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7921-0120","authenticated-orcid":true,"given":"Ayham","family":"Al Afif","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology-Head and Neck Surgery, Dalhousie University, QEII Health Sciences Centre, 3rd Floor Dickson Building, 5820 University Avenue, Halifax, Nova Scotia, Canada B3H 1Y9"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1186-2146","authenticated-orcid":true,"given":"Martin","family":"Bullock","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dalhousie University, Sir Charles Tupper Medical Building, Room 11B, 5850 College Street, P.O. Box 15000, Halifax, Nova Scotia, Canada B3H 4R2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5226-3174","authenticated-orcid":true,"given":"Martin","family":"Corsten","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology-Head and Neck Surgery, Dalhousie University, QEII Health Sciences Centre, 3rd Floor Dickson Building, 5820 University Avenue, Halifax, Nova Scotia, Canada B3H 1Y9"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2015.11.017"},{"first-page":"349","volume-title":"Secondary neoplasms","year":"1993","key":"2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1017\/s0022215100111788"},{"issue":"5","key":"4","first-page":"448","volume":"8","year":"1979","journal-title":"The Journal of Otolaryngology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890070604"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20040952"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2019.10.007"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000274"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31822d787c"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1988.01860180049028"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-020-0763-4"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.3390\/medicines5010016"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-020-01589-9"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-1256"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1177\/014556131109000417"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.5387\/fms.2013-14"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/RMR.0b013e3181570c3f"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410022930"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-009-0123-4"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770090256021"},{"issue":"11","key":"21","first-page":"719","volume":"15","year":"1955","journal-title":"Cancer Research"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194007000-00016"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197707)40:1<67::AID-CNCR2820400113>3.0.CO;2-F"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-006-0075-2"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100128452"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100105"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1611"}],"container-title":["Case Reports in Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2020\/1543129.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2020\/1543129.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cris\/2020\/1543129.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T23:32:02Z","timestamp":1596497522000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cris\/2020\/1543129\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":27,"alternative-id":["1543129","1543129"],"URL":"https:\/\/doi.org\/10.1155\/2020\/1543129","relation":{},"ISSN":["2090-6900","2090-6919"],"issn-type":[{"type":"print","value":"2090-6900"},{"type":"electronic","value":"2090-6919"}],"subject":[],"published":{"date-parts":[[2020,8,3]]}}}