{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T15:02:51Z","timestamp":1761490971067,"version":"3.37.3"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Agency Issued Joint Fund","award":["[2010]3169"],"award-info":[{"award-number":["[2010]3169"]}]},{"DOI":"10.13039\/501100010265","name":"Guizhou Medical University","doi-asserted-by":"publisher","award":["[2010]3169"],"award-info":[{"award-number":["[2010]3169"]}],"id":[{"id":"10.13039\/501100010265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2020,3,20]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic> To investigate the diagnostic value of interferon-gamma release assays combined with multiple indicators for tuberculous peritonitis. <jats:italic>Methods.<\/jats:italic> Patients who were admitted to the hospital due to suspected tuberculous peritonitis were prospectively included during the 30-month study period. Moreover, healthy individuals were recruited and included in the control group. All the study participants were assessed using various indexes, such as interferon-gamma release assays. <jats:italic>Results.<\/jats:italic> A total of 180 patients with suspected tuberculous peritonitis were enrolled, and 24 were excluded. 73 patients with a confirmed diagnosis of tuberculous peritonitis were included in the tuberculous peritonitis group, 83 patients with other diseases in the other-disease control group, and 52 healthy individuals in the control group. Moreover, 83 patients in the other-disease control group and 52 participants in the control group were identified as 135 nontuberculous peritonitis patients. The area under the receiver operating characteristics curve for the QuantiFERON-TB test was 0.851 (95% confidence interval: 0.799\u20130.903), and the optimal cutoff value was 0.55\u2009IU\/mL, which corresponds to a sensitivity and specificity of 86.30% and 80.00%, respectively. The receiver operating characteristic curves for the combination of the QuantiFERON-TB test and the use of erythrocyte sedimentation rate, serum adenosine deaminase level, serum cancer antigen 125 level, and hypersensitive C-reactive protein level had an area under the curve of 0.859 (95% confidence interval: 0.809\u20130.909), with a sensitivity and specificity of 97.26% and 62.96%, respectively. <jats:italic>Conclusions.<\/jats:italic> The combined use of the QuantiFERON-TB test and multiple indexes can significantly improve the accuracy of diagnosing tuberculous peritonitis.<\/jats:p>","DOI":"10.1155\/2020\/2056168","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T23:30:43Z","timestamp":1584747043000},"page":"1-10","source":"Crossref","is-referenced-by-count":6,"title":["Diagnostic Value of Interferon-Gamma Release Assays Combined with Multiple Indicators for Tuberculous 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