{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T12:58:01Z","timestamp":1762001881577,"version":"3.40.5"},"reference-count":7,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T00:00:00Z","timestamp":1581379200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Dermatological Medicine"],"published-print":{"date-parts":[[2020,2,11]]},"abstract":"<jats:p>Syphilis is a sexually transmitted disease caused by <jats:italic>Treponema pallidum<\/jats:italic>. The signs and symptoms of syphilis vary depending on which of the four stages it presents. The primary stage of syphilis classically presents with a painless ulcer (chancre). We report a case of the extragenital chancre on the nipple which is examined from skin biopsy and immunohistochemistry. This case showed that it is important to identify the special site\u2019s pruritus erythema by pathology and serological examination.<\/jats:p>","DOI":"10.1155\/2020\/2391907","type":"journal-article","created":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T18:30:50Z","timestamp":1581445850000},"page":"1-3","source":"Crossref","is-referenced-by-count":4,"title":["A Case of Secondary Syphilis with the Extragenital Chancre on the Nipple"],"prefix":"10.1155","volume":"2020","author":[{"given":"Xiao Yan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Juliandri","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi Jing","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia Wen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da-Guang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7172-5277","authenticated-orcid":true,"given":"Yang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.73"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2012.02814.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12818"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12491"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01560.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.7538"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1786"}],"container-title":["Case Reports in Dermatological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2020\/2391907.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2020\/2391907.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2020\/2391907.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T18:30:51Z","timestamp":1581445851000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cridm\/2020\/2391907\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,11]]},"references-count":7,"alternative-id":["2391907","2391907"],"URL":"https:\/\/doi.org\/10.1155\/2020\/2391907","relation":{},"ISSN":["2090-6463","2090-6471"],"issn-type":[{"type":"print","value":"2090-6463"},{"type":"electronic","value":"2090-6471"}],"subject":[],"published":{"date-parts":[[2020,2,11]]}}}