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Pheochromocytoma is a rare catecholamine\u2010secreting tumour arising from chromaffin cells within the adrenal medulla or extra\u2010adrenal paraganglia. The pathognomonic quartet of paroxysmal hypertension, palpitations, headache, and diaphoresis is rarely present, and diagnosis is often delayed. We describe a 43\u2010year\u2010old formerly healthy patient with an adrenal pheochromocytoma, presenting as an \u201cinverted\u201d takotsubo syndrome complicated with acute heart failure and pulmonary oedema.<\/jats:p>","DOI":"10.1155\/2020\/2521046","type":"journal-article","created":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T19:31:08Z","timestamp":1584473468000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Acute Heart Failure as a First Presentation of Pheochromocytoma Complicated with \u201cInverted\u201d Takotsubo Syndrome"],"prefix":"10.1155","volume":"2020","author":[{"given":"Jerrold","family":"Spapen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3906-264X","authenticated-orcid":false,"given":"Jeroen","family":"de Filette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stijn","family":"Lochy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert","family":"Spapen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,17]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy076"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy077"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1530\/eje-15-0483"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.07.072"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-019-02035-3"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.03.543"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.03.019"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066614552992"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2020\/2521046.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2020\/2521046.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2020\/2521046","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T23:57:26Z","timestamp":1762473446000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2020\/2521046"}},"subtitle":[],"editor":[{"given":"Wayne V.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1155\/2020\/2521046"],"URL":"https:\/\/doi.org\/10.1155\/2020\/2521046","archive":["Portico"],"relation":{},"ISSN":["2090-6501","2090-651X"],"issn-type":[{"value":"2090-6501","type":"print"},{"value":"2090-651X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"2020-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2521046"}}