{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:35:59Z","timestamp":1792802159626,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":327,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["303077\/2017-4 CNPq 2018-20"],"award-info":[{"award-number":["303077\/2017-4 CNPq 2018-20"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Despite the strong evidence on the cardiac and renal damages after chronic exposure to cigarette smoke, there is a paucity of data on its short\u2010term effects. The study evaluated the short\u2010term effects of cigarette smoking on left ventricular (LV) remodeling, <jats:italic>in vitro<\/jats:italic> myocardial and renal function. Female <jats:italic>Wistar<\/jats:italic> rats were randomized to control (C) and cigarette smoking rats for eight weeks. Physical capacity was assessed using an adapted model of exhaustive swim; left ventricle (LV) morphology and function were also evaluated. Renal function was assessed by creatinine clearance and urine protein. The <jats:italic>in vitro<\/jats:italic> myocardial performance was analyzed in isolated papillary muscles. Rats exhibited reduced physical capacity after short\u2010term cigarette smoking. Although there was no change on LV function, reduced chamber diameter was found in the smoking group associated with an increased LV wall thickness. There was augmented cardiac mass compared to C that was confirmed by increased cardiomyocyte nucleus volume, but <jats:italic>in vitro<\/jats:italic> myocardial performance and renal function were unchanged. A short\u2010term cigarette smoking induces cardiac remodeling without abnormalities in function. The smoking group still preserved renal function and <jats:italic>in vitro<\/jats:italic> myocardial performance. However, the reduced physical capacity may suggest an impairment of the cardiac reserve.<\/jats:p>","DOI":"10.1155\/2020\/2589892","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T01:38:12Z","timestamp":1606181892000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Short\u2010Term Cigarette Smoking in Rats Impairs Physical Capacity and Induces Cardiac Remodeling"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3993-8277","authenticated-orcid":false,"given":"Danilo Sales","family":"Bocalini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"da Silva Luiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kleiton Augusto Santos","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey Jorge","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata Andrade","family":"Avila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Soares","family":"Leopoldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula","family":"Lima-Leopoldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia Regina Holanda","family":"da Cunha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Jose F.","family":"Tucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199403313301307"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-0620(03)00079-3"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00056.x"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.70.6.2697"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0066-782x2005000400009"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntw180"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathophys.2018.04.003"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2008.08.009"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113739"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/15.7.938"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2003.00231.x"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13059"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-010-1406-x"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055363"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1139\/Y10-062"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.06.026"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.50.643"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2016.07.003"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0066-782x2003001100002"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105296"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/1359786810382057"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01755.x"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0012-3692(15)31272-1"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322008000400005"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.2114\/ahs1983.12.195"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000064955.31005.E0"},{"key":"e_1_2_9_27_2","first-page":"55","article-title":"Evaluation of the tolerance to the effort in smoking individuals","volume":"20","author":"Trisltz C. M.","year":"2017","journal-title":"Fisioterapia em Movimento"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-199927050-00001"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1080\/08958370701883821"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.112.1.289"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-004-0406-x"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1982.10667543"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn333"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1999.tb00091.x"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1969.00300160097016"},{"key":"e_1_2_9_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00230871"},{"key":"e_1_2_9_37_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.1.248"},{"key":"e_1_2_9_38_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641969209036186"},{"key":"e_1_2_9_39_2","doi-asserted-by":"publisher","DOI":"10.1177\/1470320315576256"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2020\/2589892.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2020\/2589892.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2020\/2589892","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T11:42:48Z","timestamp":1735645368000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2020\/2589892"}},"subtitle":[],"editor":[{"given":"Toshiyuki","family":"Sawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1155\/2020\/2589892"],"URL":"https:\/\/doi.org\/10.1155\/2020\/2589892","archive":["Portico"],"relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"2020-06-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2589892"}}