{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:19:20Z","timestamp":1790565560831,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T00:00:00Z","timestamp":1589414400000},"content-version":"vor","delay-in-days":134,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>The oral cavity is one of the most complex microbial environments; however, the complex nature of the salivary microbiota and the level of inorganic anions in the saliva of subjects with and without gastroesophageal reflux disease (GERD) are poorly understood. The primary goals of this pilot research were to assess differences in salivary bacterial community composition and inorganic anion concentrations between patients with GERD and GERD\u2010free people. Thus, the salivary microbiota within both groups was dominated by these genera: Streptococcus, Prevotella, Porphyromonas, Veillonella, Neisseria, Haemophilus, Fusobacterium, Rothia, and Leptotrichia. However, the relative abundances of the genera Actinomyces, Atopobium, Stomatobaculum, Ruminococcaceae_[G\u20102], Veillonella, and Leptotrichia were significantly higher in the saliva samples of patients with GERD, while the genera Porphyromonas, Gemella, Peptostreptococcus, and Neisseria were less abundant in this group. The concentrations of chloride, phosphate, and sulphate ions in the human saliva varied among all subjects and sampling time. These results broaden our knowledge of the salivary microbial community composition and chemistry of saliva of patients with GERD and GERD\u2010free individuals.<\/jats:p>","DOI":"10.1155\/2020\/2681791","type":"journal-article","created":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T23:40:20Z","timestamp":1589499620000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Comparison of the Microbiota and Inorganic Anion Content in the Saliva of Patients with Gastroesophageal Reflux Disease and Gastroesophageal Reflux Disease\u2010Free Individuals"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2777-843X","authenticated-orcid":false,"given":"Elvira E.","family":"Ziganshina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ildar I.","family":"Sagitov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramilya F.","family":"Akhmetova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulshat T.","family":"Saleeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey P.","family":"Kiassov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalya E.","family":"Gogoleva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena I.","family":"Shagimardanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6296-8955","authenticated-orcid":false,"given":"Ayrat M.","family":"Ziganshin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,14]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1989.0211"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep10948"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.16-0856"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1532-3382(12)70006-4"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12223-014-0342-2"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-20085-x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2013.10.006"},{"key":"e_1_2_9_8_2","first-page":"722","article-title":"What is the critical pH and why does a tooth dissolve in acid?","volume":"69","author":"Dawes C.","year":"2003","journal-title":"Journal of the Canadian Dental Association"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.2174\/1874210601812010406"},{"key":"e_1_2_9_10_2","first-page":"1030","article-title":"Fluorides \u2013 mode of action and recommendations for use","volume":"122","author":"Lussi A.","year":"2012","journal-title":"Schweizerische Monatsschrift f\u00fcr Zahnmedizin"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-5712(96)00068-1"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v5.i3.105"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.18043\/ncm.77.3.202"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-28032012000300009"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.17116\/stomat201897323"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/6765438"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27342-z"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.f.303"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00542-10"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00062-07"},{"key":"e_1_2_9_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.03534-14"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12668-016-0270-5"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8184160"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8106491"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2019.01.015"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-815249-2.00009-9"},{"key":"e_1_2_9_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118655252.ch28"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.027284-0"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/159625"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.03133-13"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4557-4801-3.00249-6"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/0928-8244(93)90093-J"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.000294"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-9-259"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-35-3-369"},{"key":"e_1_2_9_36_2","volume-title":"Atlas of Oral Microbiology: from Healthy Microflora to Disease","author":"Zhou X.","year":"2015"},{"key":"e_1_2_9_37_2","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.118317"},{"key":"e_1_2_9_38_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5027283"},{"key":"e_1_2_9_39_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.042812-0"},{"key":"e_1_2_9_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.2.558-563.2003"},{"key":"e_1_2_9_41_2","doi-asserted-by":"publisher","DOI":"10.4056\/sigs.29547"},{"key":"e_1_2_9_42_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-50-11-947"},{"key":"e_1_2_9_43_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2007.01371.x"},{"key":"e_1_2_9_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2004.05.002"},{"key":"e_1_2_9_45_2","volume-title":"Saliva and oral health","author":"Edgar W. M.","year":"1996"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2020\/2681791.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2020\/2681791.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2020\/2681791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T13:51:18Z","timestamp":1735653078000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2020\/2681791"}},"subtitle":[],"editor":[{"given":"Lucia","family":"Lopalco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1155\/2020\/2681791"],"URL":"https:\/\/doi.org\/10.1155\/2020\/2681791","archive":["Portico"],"relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"2019-12-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2681791"}}