{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:16:56Z","timestamp":1780730216300,"version":"3.54.1"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T00:00:00Z","timestamp":1582243200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2020,2,21]]},"abstract":"<jats:p>Gastric xanthelasma (GX) is a rare tumor-like lesion customarily found as an incidental finding due to its asymptomatic appearance. Grossly, it is a well-marked yellow-white plaque created in the lamina propria by microscopic clusters of foamy macrophages. Xanthelasma is rarely correlated with gastric hyperplastic polyps; gastric xanthomas are rare benign lesions that appear to be associated with inflammation of the gastric mucosa. Etiopathogenesis is also unclear, but it has been suggested to be involved in chronic gastritis, infection with <jats:italic>Helicobacter pylori<\/jats:italic> (<jats:italic>H. pylori<\/jats:italic>), diabetes mellitus, and hyperlipidemia. The gastric xanthoma prevalence ranges from 0.23% to 7%. Orth first described the condition in 1887. It has been found that xanthelasmas are associated with chronic gastritis, gastrointestinal anastomosis, intestinal metaplasia, and <jats:italic>H. pylori<\/jats:italic> infection. These lesions predispose patients to gastric cancer conditions. Xanthoma (GX) was reported to be a predictive marker for early gastric cancer. However, the effectiveness of these scores and xanthoma (GX) as predictive markers for early gastric cancer detected after <jats:italic>H. pylori<\/jats:italic> eradication remains unknown.<\/jats:p>","DOI":"10.1155\/2020\/3578927","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T18:34:35Z","timestamp":1582310075000},"page":"1-7","source":"Crossref","is-referenced-by-count":19,"title":["Gastric Xanthoma Associated with Gastric Cancer Development: An Updated Review"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5363-6024","authenticated-orcid":true,"given":"Faycal Awaleh","family":"Moumin","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5395-2273","authenticated-orcid":true,"given":"Abdimajid Ahmed","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdirahman Ahmed","family":"Osman","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4169-4531","authenticated-orcid":true,"given":"Jianting","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-003-1288-3"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.488_y.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i34.4598"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-015-1081-0"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12512"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0572-8"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.1996.tb03658.x"},{"issue":"3","key":"8","first-page":"167","volume":"16","year":"2005","journal-title":"The Turkish Journal of Gastroenterology: The Official Journal of Turkish Society of Gastroenterology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1013005"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199411000-00014"},{"issue":"3","key":"11","first-page":"181","volume":"6","year":"2010","journal-title":"Gastroenterology & Hepatology"},{"issue":"8","key":"12","first-page":"639","volume":"102","year":"1989","journal-title":"Chinese Medical Journal"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1080\/003655299750026344"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.5009\/gnl17136"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.05293.x"},{"issue":"1","key":"16","first-page":"42","volume":"61","year":"2010","journal-title":"Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/mpg.0b013e3181e2c6f8"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8566582"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/231830"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2003.02844.x"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.1998.tb03901.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.5946\/ce.2012.45.4.412"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/797264"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1159\/000325898"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0348-1"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1001\/jama.210.13.2381"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1158\/ajc.1935.477"},{"key":"28","first-page":"149","volume":"35","year":"1987","journal-title":"Archives d\u2019Anatomie et de Cytologie Pathologiques"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-010-4502-y"},{"issue":"9","key":"30","first-page":"929","volume":"114","year":"1990","journal-title":"Archives of Pathology & Laboratory Medicine"},{"issue":"11","key":"31","first-page":"1610","volume":"106","year":"2009","journal-title":"Nihon Shokakibyo Gakkai Zasshi"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(99)80224-1"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i43.7756"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(93)90173-2"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1007\/bf01303212"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.139"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.12.045"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1111\/cas.12043"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1677\/erc-09-0087"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1172\/jci112295"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(96)90013-6"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1007\/s005350050091"},{"issue":"10","key":"43","first-page":"1100","volume":"121","year":"1997","journal-title":"Archives of Pathology & Laboratory Medicine"},{"issue":"1","key":"44","first-page":"45","volume":"31","year":"2010","journal-title":"Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255944"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1503967"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2014.05.020"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v9.i8.327"}],"container-title":["Canadian Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2020\/3578927.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2020\/3578927.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjgh\/2020\/3578927.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T18:35:15Z","timestamp":1582310115000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cjgh\/2020\/3578927\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,21]]},"references-count":48,"alternative-id":["3578927","3578927"],"URL":"https:\/\/doi.org\/10.1155\/2020\/3578927","relation":{},"ISSN":["2291-2789","2291-2797"],"issn-type":[{"value":"2291-2789","type":"print"},{"value":"2291-2797","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,21]]}}}