{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:38:06Z","timestamp":1747190286604,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T00:00:00Z","timestamp":1595721600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Korea Institute of Drug Safety and Risk Management"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Therapeutics"],"published-print":{"date-parts":[[2020,7,26]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Severe hypoglycemia can be life-threatening; therefore, it is important to identify the characteristics of the hypoglycemic patients. The aim of this study is to analyze the type and characteristics of diabetic patients with hypoglycemia who visited an emergency room. <jats:italic>Methods<\/jats:italic>. We included diabetic patients with hypoglycemia who visited the emergency room of St. Mary\u2019s Hospital in Seoul from January 2009 to August 2018 in the study. Hypo_S group patients visited the emergency room once whereas Hypo_M group patients visited twice or more. We also compared the incidence of cardiovascular disease between the groups within 5 years after hypoglycemia. <jats:italic>Results<\/jats:italic>. A total of 843 patients were included in this study, with a mean age of <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>71<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>14<\/mml:mn><\/mml:math> years and average glycated hemoglobin (HbA1c) level of <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>6.7<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>1.4<\/mml:mn><mml:mi>%<\/mml:mi><\/mml:math>. For patients with hypoglycemia, lower body mass index, lower HbA1c, shorter diabetes duration, and lower glomerular filtration rate have a statistically significant relationship with patient characteristics in the emergency room group (all <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). Hypoglycemia symptoms were most frequently observed between 6:00 and 12:00 am (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). Cardiovascular diseases within 5 years after discharge were more frequent in the Hypo_S group than in the Hypo_M group; however, there was no statistical significance. The frequency of aneurysms was significantly higher in patients with hypoglycemia than in other patients in the emergency room (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>). <jats:italic>Conclusion<\/jats:italic>. Relatively thin older patients with a diabetes duration shorter than 10 years and good blood sugar control showed higher frequency of visits to the emergency room due to hypoglycemia. For these patients, medical staff should always be mindful of their susceptibility to hypoglycemia when prescribing insulin or OHA and educate them on the prevention of hypoglycemia.<\/jats:p>","DOI":"10.1155\/2020\/3612607","type":"journal-article","created":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T23:30:43Z","timestamp":1595806243000},"page":"1-9","source":"Crossref","is-referenced-by-count":2,"title":["Characteristics of Hypoglycemic Diabetic Patients Visiting the Emergency Room"],"prefix":"10.1155","volume":"2020","author":[{"given":"Tong Min","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunah","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Sookmyung Women\u2019s University, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3964-3877","authenticated-orcid":true,"given":"Seung-Hwan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"},{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Hyoung","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"},{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunyong","family":"Lee","sequence":"additional","affiliation":[{"name":"Clinical Research Coordinating Center, Catholic Medical Center, The Catholic University of Korea, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeon Woo","family":"Yim","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun-Ho","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"},{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7002-7300","authenticated-orcid":true,"given":"Hun-Sung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"},{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.6.1902"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.4093\/jkd.2016.17.3.202"},{"issue":"24","key":"3","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1056\/NEJMoa0802743","volume":"358","year":"2008","journal-title":"The New England Journal of 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