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Currently, several types of acupuncture have been developed but it is not clear which type is suitable for FD. Currently, doctors often rely on experience to decide which form of acupuncture to apply. Herein, we employed network meta\u2010analysis (NMA) to compare the effectiveness of various methods of acupuncture in the treatment of functional dyspepsia. <jats:italic>Methods<\/jats:italic>. We searched for randomized controlled trials (RCTs) of acupuncture treatments for functional dyspepsia in seven databases; PubMed, the Cochrane Library, Embase, Wanfang database, China National Knowledge Infrastructure (CNKI) database, Chinese Science and Technique Journals (CQVIP), and Chinese Biomedical Database (CBM) from the date of database inception to October 10, 2019. Cochrane risk of bias tool was used to analyze the risk of bias of the included RCTs. Pairwise meta\u2010analyses were performed with RevMan 5.3 and the network meta\u2010analysis of the included RCTs was performed using the frequentist framework. <jats:italic>Results<\/jats:italic>. A total of 35 studies involving 3301 patients and 10 interventions were eligible for this study. NMA results showed that five types of acupuncture (manual acupuncture, acupoint application, moxibustion, acupoint catgut embedding, and warm acupuncture alone) all were superior to prokinetics (itopride, mosapride, and domperidone) and sham acupuncture in terms of improving the symptoms of functional dyspepsia. Specifically, manual acupuncture and electroacupuncture were more effective in improving the MOS 36 Item Short\u2010Form Health Survey (SF\u201036) compared to itopride and sham acupuncture, and electroacupuncture was the best among the three acupuncture therapies (acupuncture, electroacupuncture, and acupoint catgut embedding). Moxibustion and manual acupuncture were more effective in improving Nepean Dyspepsia Life Quality Index (NDLQI) compared to itopride, domperidone, and sham acupuncture; moxibustion ranks first among the three acupuncture therapies (acupuncture, electroacupuncture, moxibustion). <jats:italic>Conclusions<\/jats:italic>. These results showed that manual acupuncture alone was the most effective therapy for FD. It should, therefore, be considered as an alternative treatment for FD patients who are unresponsive to prokinetics or intolerant to the adverse effects of prokinetics. We recommend further multiple centers and high\u2010quality RCT studies to confirm the present findings.<\/jats:p>","DOI":"10.1155\/2020\/3872919","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T23:31:26Z","timestamp":1584660686000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Efficacy Comparison of Different Acupuncture Treatments for Functional Dyspepsia: A Systematic Review with Network Meta\u2010Analysis"],"prefix":"10.1155","volume":"2020","author":[{"given":"Jinhuan","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongfeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yirong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3100-0786","authenticated-orcid":false,"given":"Haibo","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,19]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.011"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2011.17.3.235"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.5056\/jnm14165"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01262.x"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12355"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2012.05128.x"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11377-017-0143-7"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2012.255"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2018.0222"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1517\/14728214.2015.1009827"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.851193"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/pds.3814"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-12-87"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2010.03.007"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13381"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.53"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12532"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2014.11.011"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2015.07.007"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2014.0400"},{"key":"e_1_2_9_21_2","first-page":"100","article-title":"The effect of acupuncture and moxibustion on functional dyspepsia compared with prokinetic agents: a meta-analysis","volume":"23","author":"Wu X. 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