{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:56:36Z","timestamp":1753887396285,"version":"3.41.2"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T00:00:00Z","timestamp":1603065600000},"content-version":"vor","delay-in-days":292,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Nanjing Science and Technology Plan","award":["201803065","JD 2019SZ15"],"award-info":[{"award-number":["201803065","JD 2019SZ15"]}]},{"name":"Science and Technology Project of Jiangsu Traditional Chinese Medicine Bureau","award":["201803065","JD 2019SZ15"],"award-info":[{"award-number":["201803065","JD 2019SZ15"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To explore the proportion and characteristic of Chinese adults meeting <jats:italic>The Systolic Blood Pressure Intervention Trial<\/jats:italic> (SPRINT) eligibility criteria and assess its generalizability. <jats:italic>Method<\/jats:italic>. Our study was based on a cross\u2010sectional, population\u2010based survey with a sample of 26,093 participants aged over 20 years. The SPRINT eligibility criteria were age \u2265 50 years, elevated SBP of 130 to 180\u2009mmHg depending on the number of antihypertensive medication classes being taken, and increased cardiovascular disease (CVD) but without diabetes, history of stroke and estimated glomerular filtration rate &lt; 20\u2009ml\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>, or receiving dialysis. <jats:italic>Results<\/jats:italic>. Overall, we estimated that 4,036 (15.5%) participants would meet the SPRINT eligibility criteria. They were generally older, likely to be female, lower educational level, tended to be more overweight, and had higher Framingham risk score compared with overall population or subjects aged \u2265 50 years. Of participants eligible for SPRINT, most (56.2%) of them were not treated for hypertension, and 542 (13.4%) were not previously considered to have hypertension or need for antihypertension therapy. Among the 11,637 adults with hypertension, 3,494 (30.0%) would potentially benefit from treatment intensification. The most common antihypertensive medication class being taken was diuretic agents. <jats:italic>Conclusion<\/jats:italic>. A substantial percentage of Chinese subjects meet the SPRINT eligibility criteria. Further studies are needed to assess the cost\u2010effectiveness from treatment intensification in Chinese setting.<\/jats:p>","DOI":"10.1155\/2020\/4751756","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T01:20:14Z","timestamp":1603156814000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Eligibility of the Systolic Blood Pressure Intervention Trial (SPRINT) to the Chinese 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