{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T13:49:27Z","timestamp":1772372967799,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T00:00:00Z","timestamp":1588204800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NSF-MCB","award":["1714157"],"award-info":[{"award-number":["1714157"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Complexity"],"published-print":{"date-parts":[[2020,4,30]]},"abstract":"<jats:p>After a theory of morphogenesis in chemical cells was introduced in the 1950s, much attention had been devoted to the numerical solution of <jats:italic>reaction-diffusion<\/jats:italic> (RD) <jats:italic>partial differential equations<\/jats:italic> (PDEs). The <jats:italic>Crank\u2013Nicolson<\/jats:italic> (CN) method has been a common second-order time-stepping procedure. However, the CN method may introduce spurious oscillations for nonsmooth data unless the time step size is sufficiently small. This article studies a nonoscillatory second-order time-stepping procedure for RD equations, called a <jats:italic>variable-<\/jats:italic><mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>\u03b8<\/mml:mi><\/mml:math><jats:italic>method<\/jats:italic>, as a perturbation of the CN method. In each time level, the new method detects points of potential oscillations to implicitly resolve the solution there. The proposed time-stepping procedure is nonoscillatory and of a second-order temporal accuracy. Various examples are given to show effectiveness of the method. The article also performs a sensitivity analysis for the numerical solution of biological pattern forming models to conclude that the numerical solution is much more sensitive to the spatial mesh resolution than the temporal one. As the spatial resolution becomes higher for an improved accuracy, the CN method may produce spurious oscillations, while the proposed method results in stable solutions.<\/jats:p>","DOI":"10.1155\/2020\/5163704","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T23:35:27Z","timestamp":1588289727000},"page":"1-15","source":"Crossref","is-referenced-by-count":4,"title":["A Nonoscillatory Second-Order Time-Stepping Procedure for Reaction-Diffusion Equations"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1205-6664","authenticated-orcid":true,"given":"Philku","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Mathematics and Statistics, Mississippi State University, Starkville, Mississippi State, MS 39762, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7580-6792","authenticated-orcid":true,"given":"George V.","family":"Popescu","sequence":"additional","affiliation":[{"name":"Institute for Genomics, Biocomputing and Biotechnology, Mississippi State University, Starkville, Mississippi State, MS 39762, USA"},{"name":"The National Institute for Laser, Plasma & Radiation Physics, 077126 M\u0103gurele, Ilfov, Romania"}]},{"given":"Seongjai","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Statistics, Mississippi State University, Starkville, Mississippi State, MS 39762, USA"}]}],"member":"311","reference":[{"issue":"641","key":"1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1098\/rstb.1952.0012","volume":"237","year":"1952","journal-title":"Philosophical Transactions of the Royal Society of London. 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