{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:49:01Z","timestamp":1792601341110,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T00:00:00Z","timestamp":1589932800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Reseau International des Instituts Pasteur"},{"DOI":"10.13039\/501100003762","name":"Institut Pasteur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Interdisciplinary Perspectives on Infectious Diseases"],"published-print":{"date-parts":[[2020,5,20]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Leptospirosis is an anthropozoonotic reemerging neglected infectious disease underreported in most developing countries. A cross-sectional study was performed between 17 and 23 February 2014 to estimate the seroprevalence of leptospirosis among high-risk populations in Casablanca (Morocco). <jats:italic>Methods<\/jats:italic>. A total of 490 human serum samples (97.6% males) were collected in 3 high-risk occupational sites including the biggest meat slaughterhouse (<jats:italic>n<\/jats:italic>\u2009=\u2009208), a poultry market (<jats:italic>n<\/jats:italic>\u2009=\u2009121), and the fish market (<jats:italic>n<\/jats:italic>\u2009=\u2009161). A total of 125 human blood samples were also collected from the general population and used in this study as a control group. To detect the presence of anti-<jats:italic>Leptospira<\/jats:italic>, sera were screened with in-house IgG and IgM enzyme-linked immunosorbent assay (ELISA). Positive samples were tested by Microscopic Agglutination Technique (MAT) using a panel of 24 serovar cultures and cut point of 1\u2009:\u200925. <jats:italic>Results<\/jats:italic>. Seroprevalence of leptospirosis among the control group was 10.4% (13\/125). A high seropositivity among the overall seroprevalence of 24.1% (118\/490) was observed in the high-risk groups of which 7.3% (36\/490), 13.7% (67\/490), and 3.1% (15\/490) were for anti-<jats:italic>Leptospira<\/jats:italic> IgM, IgG, and both IgG and IgM antibodies, respectively. Most of the positive individuals were occupationally involved in poultry (37.2%), followed by the market fish (26.1%) and the meat slaughterhouse (14.9%) workers. Among all ELISA-positive serum samples, 20.3% (<jats:italic>n<\/jats:italic>\u2009=\u200924) had positive MAT responses, of which the Icterohaemorrhagiae (<jats:italic>n<\/jats:italic>\u2009=\u20097) is the most common infecting serogroup followed by Javanica (4), Australis (2), and Sejroe, Mini, and Panama (one in each). In the remaining 8 MAT-positive sera, MAT showed equal titers against more than one serogroup. <jats:italic>Conclusion<\/jats:italic>. Individuals engaged in risk activities are often exposed to leptospiral infection. Therefore, control and prevention policies toward these populations are necessary.<\/jats:p>","DOI":"10.1155\/2020\/5236045","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T23:35:02Z","timestamp":1590017702000},"page":"1-8","source":"Crossref","is-referenced-by-count":11,"title":["Seroprevalence of Leptospirosis among High-Risk Individuals in Morocco"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7541-4396","authenticated-orcid":true,"given":"Mohamed","family":"El Azhari","sequence":"first","affiliation":[{"name":"Laboratory of Bacteriology, Institut Pasteur Du Maroc, MoH, 1, Place Charles Nicolle, Casablanca 20360, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Picardeau","sequence":"additional","affiliation":[{"name":"National Reference Center and The WHO Collaborating Center for Leptospirosis, Institut Pasteur, Paris, 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