{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T23:41:20Z","timestamp":1782258080663,"version":"3.54.5"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,10,26]]},"abstract":"<jats:p>Purpose. To compare the corneal biomechanical properties between post-LASIK ectasia and primary keratoconus. Methods. A total of 42 eyes of 42 patients with matching age and central corneal thickness (CCT) were divided into two groups according to diagnosis of post-LASIK ectasia (PLE group; n\u2009=\u200921; age range: 22\u201347 years) and primary keratoconus (KC group; n\u2009=\u200921; age range: 21\u201347 years). The corneal biomechanical properties were assessed using Scheimpflug-based technology (Corvis ST; Oculus Optikger\u00e4te, Wetzlar, Germany). The paired t-test and linear regression analysis were performed. Results. The PLE group had significantly higher mean stiffness parameter at the first applanation (SP-A1; 76.65\u2009\u00b1\u200921.66 vs 52.72\u2009\u00b1\u200913.65, <jats:inline-formula>\n                     <a:math xmlns:a=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                        <a:mi>p<\/a:mi>\n                        <a:mo>\u2264<\/a:mo>\n                        <a:mn>0.001<\/a:mn>\n                     <\/a:math>\n                  <\/jats:inline-formula>) and mean stress-strain index (SSI) (SSI: 0.78\u2009\u00b1\u20090.16 versus 0.64\u2009\u00b1\u20090.12, <jats:inline-formula>\n                     <c:math xmlns:c=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                        <c:mi>p<\/c:mi>\n                        <c:mo>=<\/c:mo>\n                        <c:mn>0.001<\/c:mn>\n                     <\/c:math>\n                  <\/jats:inline-formula>) than the KC group. SP-A1 was positively correlated with CCT in the PLE group (Pearson\u2019s r\u2009=\u20090.816, <jats:inline-formula>\n                     <e:math xmlns:e=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                        <e:mi>p<\/e:mi>\n                        <e:mo>\u2264<\/e:mo>\n                        <e:mn>0.001<\/e:mn>\n                     <\/e:math>\n                  <\/jats:inline-formula>), but not in the KC group (Pearson\u2019s r\u2009=\u2009\u22120.014, <jats:inline-formula>\n                     <g:math xmlns:g=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                        <g:mi>p<\/g:mi>\n                        <g:mo>=<\/g:mo>\n                        <g:mn>0.952<\/g:mn>\n                     <\/g:math>\n                  <\/jats:inline-formula>). No statistical correlation was observed between SSI and CCT in either group (Pearson\u2019s r\u2009=\u20090.292, <jats:inline-formula>\n                     <i:math xmlns:i=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                        <i:mi>p<\/i:mi>\n                        <i:mo>=<\/i:mo>\n                        <i:mn>0.199<\/i:mn>\n                     <\/i:math>\n                  <\/jats:inline-formula>, and Pearson\u2019s r\u2009=\u20090.004, <jats:inline-formula>\n                     <k:math xmlns:k=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\">\n                        <k:mi>p<\/k:mi>\n                        <k:mo>=<\/k:mo>\n                        <k:mn>0.985<\/k:mn>\n                     <\/k:math>\n                  <\/jats:inline-formula>, respectively). Conclusions. In our case series, KC manifested more severe than PLE in biomechanical properties. Since SSI measurements were independent of corneal thickness, it can be used for corneal biomechanical assessment.<\/jats:p>","DOI":"10.1155\/2020\/5291485","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T01:05:19Z","timestamp":1603760719000},"page":"1-8","source":"Crossref","is-referenced-by-count":10,"title":["Comparison of Corneal Biomechanical Properties between Post-LASIK Ectasia and Primary Keratoconus"],"prefix":"10.1155","volume":"2020","author":[{"given":"Wuxiao","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Myopia, Fudan University, Shanghai, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Myopia, Fudan University, Shanghai, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijun","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Myopia, Fudan University, Shanghai, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Myopia, Fudan University, Shanghai, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Jhanji","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aruma","family":"Aruma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Myopia, Fudan University, Shanghai, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3465-1579","authenticated-orcid":true,"given":"Xingtao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Myopia, Fudan University, Shanghai, China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1080\/08820538.2019.1569075"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0000000000000408"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2019.0143"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.06.008"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.04.013"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14450"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20170213-01"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20190226-01"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20160629-01"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20181012-01"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.08.054"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-018-0594-5"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310355"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-019-01026-0"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20080101-16"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-19677"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-39182-6"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.3928\/1081597x-20161221-03"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00105"}],"container-title":["Journal 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