{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T13:44:32Z","timestamp":1768830272710,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":266,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Youth National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81904279"],"award-info":[{"award-number":["81904279"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"Youth National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["YB2017041"],"award-info":[{"award-number":["YB2017041"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Project of Jiangsu Provincial Bureau of Traditional Chinese Medicine","award":["81904279"],"award-info":[{"award-number":["81904279"]}]},{"name":"Science and Technology Project of Jiangsu Provincial Bureau of Traditional Chinese Medicine","award":["YB2017041"],"award-info":[{"award-number":["YB2017041"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To observe the influence of the catgut\u2010embedding method in Du Meridian acupoint on the mental and psychological state of patients with gastroesophageal reflux disease (GERD) and analyze its possible mechanism. <jats:italic>Methods<\/jats:italic>. According to the random number table, 60 patients with GERD were randomly divided into groups of acupoint catgut embedding and Western medicine, 30 cases in each group. The acupoint group was given catgut embedment in the positive reaction points along the Du Meridian, while the Western medicine group received lansoprazole tablet. They were both treated for six weeks. Scores of Gastroesophageal Reflux Disease Questionnaire (GerdQ), Zung\u2019s Self\u2010Rating Anxiety Scale (SAS), Zung\u2019s Self\u2010Rating Depression Scale (SDS), and Health\u2010Related Quality of Life Scale for GERD (GERD\u2010HRQL) were measured before and after treatment to analyze and evaluate the differences of symptom scores and mental and psychological conditions between the two groups. <jats:italic>Results<\/jats:italic>. (1) The scores of GerdQ, GERD\u2010HRQL, SAS, and SDS in the two groups both significantly decreased after treatment (<jats:italic>P<\/jats:italic> &lt; 0.05), and those of the acupoint group were much lower than the Western medicine group (<jats:italic>P<\/jats:italic> &lt; 0.05). (2) The total effective rate was 90.00% in the acupoint group and 53.33% in the Western medicine group, with a statistically significant difference (<jats:italic>P<\/jats:italic> &lt; 0.05). (3) The correlation coefficients <jats:italic>r<\/jats:italic> between the GerdQ score and scores of SAS and SDS were 0.563 and 0.322, respectively, and those between the GERD\u2010HRQL score and scores of SAS and SDS were, respectively, 0.506 and 0.435. <jats:italic>Conclusion<\/jats:italic>. (1) The main symptoms of GERD patients, such as acid reflux and heartburn, mental and psychological condition, and quality of life, were all improved in the two groups, but the efficacy in the acupoint group is superior to that of the Western medicine group. (2) The clinical symptoms and scores of patients\u2019 quality of life are positively correlated with the degree of their anxiety and depression. (3) The acupoint catgut\u2010embedding method can effectively regulate the anxiety and depressive symptoms of patients, which complements the efficacy of proton\u2010pump inhibitors and benefits a wider range of population.<\/jats:p>","DOI":"10.1155\/2020\/5415813","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T01:55:33Z","timestamp":1600912533000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effect of Catgut Embedment in Du Meridian Acupoint on Mental and Psychological Conditions of Patients with Gastroesophageal Reflux 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