{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T23:50:25Z","timestamp":1768261825298,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:00:00Z","timestamp":1581465600000},"content-version":"vor","delay-in-days":42,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008903","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["MOHW107-TDU-B- 212-123004"],"award-info":[{"award-number":["MOHW107-TDU-B- 212-123004"]}],"id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["BM10701010021"],"award-info":[{"award-number":["BM10701010021"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["MOST 106-2321-B-039-005"],"award-info":[{"award-number":["MOST 106-2321-B-039-005"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011892","name":"Kaohsiung Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG8B1301-CRRPG8B1303"],"award-info":[{"award-number":["CMRPG8B1301-CRRPG8B1303"]}],"id":[{"id":"10.13039\/501100011892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011892","name":"Kaohsiung Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CRRPG8F0461-CRRPG8F0463"],"award-info":[{"award-number":["CRRPG8F0461-CRRPG8F0463"]}],"id":[{"id":"10.13039\/501100011892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004737","name":"National Health Research Institutes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004737","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Pyogenic liver abscess (PLA) is a potentially fatal disease that can stimulate prominent systemic inflammation. Osteoporotic hip fracture is a major complication of systemic inflammation. This study tried to determine the epidemiology of hip fractures among PLA patients. All subjects admitted due to PLA during 1999\u223c2010 were assessed, excluding the subjects with a history of high energy trauma, malignancy, and previous hip fracture. We matched the control subjects to PLA patients according to age, gender, and the coding of osteoporosis by 1\u2009:\u20094 ratio. The PLA patients had a 1.17\u2010fold risk of hip fracture than the controls (aHR\u2009=\u20091.17, 95% CI\u2009=\u20091.07\u20131.29) after adjusting for gender, age, and comorbidities. Considering death as the competing event of suicide, the PLA patients had 1.10\u2010fold suicide risk (aHR\u2009=\u20091.10, 95% CI: 1.00\u20131.21) than the control subjects under the competing risks regression model. The cumulative incidence of hip fracture was higher in the PLA cohort (log\u2010rank test, <jats:italic>p<\/jats:italic> &lt; 0.001). When compared to the controls, the fracture risk was 18.4\u2010fold (aHR\u2009=\u200918.4, 95% CI\u2009=\u200913.0\u201326.1) for the PLA patients admitted 2\u20103 times per year and 46.0\u2010fold (aHR\u2009=\u200946.0, 95% CI\u2009=\u200931.2\u201367.8) for the PLA patients admitted \u22674 times per year. The impact of PLA is more prominent among the subjects aged &lt;45 years (aHR\u2009=\u20092.81, 95% CI\u2009=\u20091.42\u20135.56). Preventive measures for hip fracture might be warranted for PLA patients.<\/jats:p>","DOI":"10.1155\/2020\/5901962","type":"journal-article","created":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T23:35:50Z","timestamp":1581550550000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Epidemiology of Hip Fracture among Subjects with Pyogenic Liver Abscess (PLA): A Nationwide Population\u2010Based 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