{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:37:16Z","timestamp":1747190236480,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ho Chi Minh City University of Technology \u2013VNU-HCM","award":["T-KHUD-2019-57"],"award-info":[{"award-number":["T-KHUD-2019-57"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Healthcare Engineering"],"published-print":{"date-parts":[[2020,9,21]]},"abstract":"<jats:p>Multispectral imaging has recently shown good performance in determining information about physiology, morphology, and composition of tissue. In the endoscopy field, many researches have shown the ability to apply multispectral or narrow-band images in surveying vascular structure based on the interaction of light wavelength with tissue composition. However, there has been no mention to assess the contrast between other components in the middle ear such as the tympanic membrane, malleus, and the surrounding area. Using CT, OCT, or ODT can clearly describe the tympanic membrane structure; nevertheless, these approaches are expensive, more complex, and time-consuming and are not suitable for most common middle ear diagnoses. Here, we show the potential of using the multispectral imaging technique to enhance the contrast of the tympanic membrane compared to the surrounding tissue. The optical absorption and scattering of biological tissues constituents are not the same at different wavelengths. In this pilot study, multiwavelength images of the tympanic membrane were captured by using the otoscope with LED light source at three distinct spectral regions: 450\u2009nm, 530\u2009nm, and 630\u2009nm. Subsequently, analyses of the intensity images as well as the histogram of these images point out that the 630\u2009nm illumination image features an evident contrast in the intensity of the tympanic membrane and malleus compared to the surrounding area. Analysis of such images could facilitate the boundary determination and segmentation of the tympanic membrane (TM) with high precision.<\/jats:p>","DOI":"10.1155\/2020\/6219845","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T23:31:20Z","timestamp":1600731080000},"page":"1-9","source":"Crossref","is-referenced-by-count":1,"title":["Application of Multispectral Imaging in the Human Tympanic Membrane"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7635-302X","authenticated-orcid":true,"given":"Tien","family":"Tran Van","sequence":"first","affiliation":[{"name":"Ho Chi Minh City University of Technology, Faculty of Applied Science, Department of Applied Physics, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"},{"name":"National Key Laboratory of Digital Control and System Engineering, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi","family":"Lu Thi Thao","sequence":"additional","affiliation":[{"name":"Ho Chi Minh City University of Technology, Faculty of Applied Science, Department of Applied Physics, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"},{"name":"National Key Laboratory of Digital Control and System Engineering, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linh","family":"Bui Mai Quynh","sequence":"additional","affiliation":[{"name":"Ho Chi Minh City University of Technology, Faculty of Applied Science, Department of Applied Physics, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cat","family":"Phan Ngoc Khuong","sequence":"additional","affiliation":[{"name":"Ho Chi Minh City University of Technology, Faculty of Applied Science, Department of Applied Physics, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"},{"name":"National Key Laboratory of Digital Control and System Engineering, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linh","family":"Huynh Quang","sequence":"additional","affiliation":[{"name":"Ho Chi Minh City University of Technology, Faculty of Applied Science, Department of Applied Physics, 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City 700 000, 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