{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:49:08Z","timestamp":1787017748692,"version":"build-2736575974"},"reference-count":138,"publisher":"Wiley","license":[{"start":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T00:00:00Z","timestamp":1607644800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oxidative Medicine and Cellular Longevity"],"published-print":{"date-parts":[[2020,12,11]]},"abstract":"<jats:p>Hypertension is a dominant risk factor for the development of cardiovascular, kidney, and eye diseases. In Africa, it increasingly leads to hospitalisation and a strain on the public health system. However, rather than modern medicine, African traditional healers are the first choice for most South Africans. Therefore, this study is aimed at gathering information on herbal remedies traditionally used for the treatment of high blood pressure in Vhavenda, South Africa, and comparing this information with reports in the literature regarding plants used to manage high blood pressure. An ethnobotanical survey was carried out in Vhembe district and its environs with 53 herbalists and indigenous people aged between 36 and 66 years from January to October 2019 using a semistructured questionnaire. The plants were collected with each respondent; they were authenticated and kept in herbarium. A total of 51 different plants were mentioned as being most commonly used for hypertension treatment. Of these, 44 plants were identified, with those from the Fabaceae family followed by plants from the Celastraceae family being commonly mentioned. Of these, the Elaeodendron transvaalense, Tabernaemontana elegans, Elephantorrhiza elephantina, and Aloe vossii were commonly cited species. According to the literature data, most of the identified plants are yet to be scientifically investigated for the treatment of hypertension, whereas only preliminary investigations have been carried out on other plants, suggesting that these preliminary investigations may have highlight promising antihypertensive activities in vitro that are indicative of their potential as antihypertensive drugs. Therefore, there is a need to scientifically investigate the antihypertensive potentials of these plants as a potential source of antihypertensive treatment and compounds.<\/jats:p>","DOI":"10.1155\/2020\/6636766","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:20:22Z","timestamp":1607732422000},"page":"1-18","source":"Crossref","is-referenced-by-count":12,"title":["Vhavenda Herbal Remedies as Sources of Antihypertensive Drugs: Ethnobotanical and Ethnopharmacological Studies"],"prefix":"10.1155","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5899-8817","authenticated-orcid":true,"given":"Gundo","family":"Mudau","sequence":"first","affiliation":[{"name":"Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Johannesburg 1709, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7580-6709","authenticated-orcid":true,"given":"Samuel","family":"Odeyemi","sequence":"additional","affiliation":[{"name":"Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Johannesburg 1709, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Dewar","sequence":"additional","affiliation":[{"name":"Department of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Johannesburg 1709, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2016.10.063"},{"key":"2","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3389\/fphar.2018.00789","article-title":"Ethnobotany of anti-hypertensive plants used in northern Pakistan","volume":"9","author":"K. Malik","year":"2018","journal-title":"Frontiers in Pharmacology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(02)00164-2"},{"issue":"2","key":"4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.56026\/imu.4.2.27","article-title":"The prevalence of hypertension and its associated risk factors in two rural communities in Penang, Malaysia","volume":"4","author":"S. R. Tee","year":"2010","journal-title":"International e-Journal of Medical Science and Education"},{"key":"5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.2147\/IJNRD.S39739","article-title":"Obesity, hypertension, and chronic kidney disease","volume":"7","author":"M. E. Hall","year":"2014","journal-title":"International Journal of Nephrology and Renovascular Disease"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.12.005"},{"key":"7","volume-title":"Curationis","author":"D. Van Rooyen","year":"2015"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czw022"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/649832"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.4314\/ajtcam.v13i2.16"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2015.07.007"},{"issue":"3","key":"12","first-page":"156","article-title":"An ethnobotanical survey of medicinal plants used by local traditional healers of Thiruvengimalai, Tiruchirapalli district, Tamil Nadu, southern India","volume":"5","author":"V. Nanadagopalan","year":"2015","journal-title":"Asian Journal of Pharmaceutical Science & Technology"},{"key":"13","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/978-94-017-9300-1_9","article-title":"Integrating indigenous knowledge with science teaching","volume-title":"Embracing Indigenous Knowledge in Science and Medical Teaching","author":"M. G. Hewson","year":"2015"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.21010\/ajtcam.v13i6.13"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/pon.4033"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12775"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjp.2015.07.030"},{"issue":"1","key":"18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13002-015-0031-5","article-title":"Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand","volume":"11","author":"K. Maneenoon","year":"2015","journal-title":"Journal of Ethnobiology and Ethnomedicine"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.11.011"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1186\/s13002-015-0075-6"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-018-1630-y"},{"key":"22","volume-title":"Traditional Health Practitioners Act 22 of 2007","author":"Government Gazette No 30660","year":"2008"},{"issue":"12","key":"23","first-page":"498","article-title":"Are there 200,000 and more traditional healers practicing in South Africa?","volume":"9","author":"G. Louw","year":"2016","journal-title":"Australasian Medical Journal"},{"issue":"4","key":"24","doi-asserted-by":"crossref","first-page":"279","DOI":"10.7196\/SAMJ.9217","article-title":"Traditional health practitioners and the authority to issue medical certificates","volume":"105","author":"B. Tshehla","year":"2015","journal-title":"South African Medical Journal"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2014.09.016"},{"key":"26","article-title":"Vhembe District Municipality (DC34)","volume-title":"Municipalities of South Africa","author":"Municipalities of South Africa","year":"2017"},{"key":"27","article-title":"Local Municipality | Statistics South Africa","author":"Statistics South Africa","year":"2011"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2017.12.013"},{"issue":"4","key":"29","doi-asserted-by":"crossref","first-page":"732","DOI":"10.3390\/molecules24040732","article-title":"Review of ethnomedicinal, phytochemical and pharmacological properties of Lannea schweinfurthii (Engl.) Engl.","volume":"24","author":"A. Maroyi","year":"2019","journal-title":"Molecules"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2007.07.006"},{"issue":"4","key":"31","first-page":"768","article-title":"Acetylcholinesterase inhibitory activity of extracts from Angolan medicinal plants","volume":"7","author":"N. A. F. Fernandes","year":"2015","journal-title":"International Journal of Pharmacognosy and Phytochemical Research"},{"issue":"27","key":"32","doi-asserted-by":"crossref","first-page":"6352","DOI":"10.5897\/JMPR10.517","article-title":"Medicinal resources of the Miombo woodlands of Urumwa, Tanzania: plants and its uses","volume":"5","author":"S. Suzana Augustino","year":"2011","journal-title":"Journal of Medicinal Plants Research"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/0378-8741(84)90099-0"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2014.09.018"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.09.057"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-13-285"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1177\/0960327108099526"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.06.051"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/340215"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytol.2017.04.015"},{"issue":"1","key":"41","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jep.2004.03.026","article-title":"New evidences of antimalarial activity of Bidens pilosa roots extract correlated with polyacetylene and flavonoids","volume":"93","author":"F. Oliveira","year":"2004","journal-title":"Journal of Ethnopharmacology"},{"issue":"8","key":"42","first-page":"355","article-title":"Isolation and characterization of dipeptide derivative and phytosterol from Capparis tomentosa Lam","volume":"3","author":"O. Akoto","year":"2008","journal-title":"Scientific Research and Essay"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.112654"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2018.11.035"},{"issue":"6","key":"45","article-title":"Cactus (Opuntia ficus-indica): a review on its antioxidants properties and potential pharmacological use in chronic diseases","volume":"2","author":"U. Osuna-Mart\u00ednez","year":"2014","journal-title":"Natural Products Chemistry & Research"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2018.10.018"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2014.06.008"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(00)00293-2"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2016.09.040"},{"key":"50","doi-asserted-by":"crossref","DOI":"10.3390\/molecules23112759","article-title":"Medicinal plants used for the traditional management of diabetes in the Eastern Cape, South Africa: pharmacology and toxicology","volume":"23","author":"S. Odeyemi","year":"2018","journal-title":"Molecules"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.04.052"},{"issue":"16","key":"52","first-page":"1695","article-title":"Cytotoxicity activity of isolated compounds from Elaeodendron transvaalense ethanol extract","volume":"4","author":"T. E. Tshikalange","year":"2010","journal-title":"Journal of Medicinal Plants Research"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2018.07.020"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.09.035"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2014.06.005"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-375688-6.10091-X"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(01)00375-0"},{"issue":"1","key":"58","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3923\/rjphyto.2018.21.34","article-title":"Phytochemical screening of root extract of Momordica boivinii and isolation of two steroids","volume":"12","author":"F. Tamiru","year":"2018","journal-title":"Research Journal of Phytochemistry"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1016\/S0254-6299(15)30321-5"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2015.08.009"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2008.06.031"},{"issue":"10, article e02677","key":"62","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2019.e02677","article-title":"Volatiles from African species of Croton (Euphorbiaceae), including new diterpenes in essential oil from Croton gratissimus","volume":"5","author":"N. J. Sadgrove","year":"2019","journal-title":"Heliyon"},{"key":"63","doi-asserted-by":"crossref","first-page":"127","DOI":"10.32604\/phyton.2011.80.127","article-title":"Population dynamics of Millettia stuhlmannii Taub. in Ha-Makhuvha, Vhembe district of Limpopo Province, South Africa","volume":"80","author":"M. Tshisikhawe","year":"2011","journal-title":"Phyton"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2015.05.009"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2018.03.009"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1016\/S0367-326X(00)00259-8"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2014.11.034"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.936"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2019.11.030"},{"issue":"24","key":"70","article-title":"Investigation of the anti-inflammatory and antinociceptive activities of Elephantorrhiza elephantina (Burch.) Skeels root extract in male rats","volume":"8","author":"V. Maphosa","year":"2009","journal-title":"African Journal of Biotechnology"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2019.07.015"},{"issue":"5","key":"72","first-page":"362","article-title":"Evaluation of in vitro antibacterial activity in Senna didymobotrya roots methanolic-aqua extract and the selected fractions against selected pathogenic microorganisms","volume":"3","author":"T. Anthoney Swamy","year":"2014","journal-title":"International Journal of Current Microbiology and Applied Sciences"},{"issue":"12, article e02924","key":"73","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2019.e02924","article-title":"Antipyretic potential of dichloromethane leaf extract of Eucalyptus globulus (Labill) and Senna didymobotrya (Fresenius) in rats models","volume":"5","author":"J. K. Mworia","year":"2019","journal-title":"Heliyon"},{"issue":"12","key":"74","doi-asserted-by":"crossref","DOI":"10.5897\/AJPP11.852","article-title":"Phytochemical screening and antibacterial activity of the leaf and root extracts of Senna italica","volume":"6","author":"Y. Dabai","year":"2012","journal-title":"African Journal of Pharmacy and Pharmacology"},{"issue":"3","key":"75","first-page":"432","article-title":"Nutritional and phytochemical screening of Senna obtusifolia indigenous to Mubi, Nigeria","volume":"2","author":"I. Y. Sudi","year":"2011","journal-title":"Advances in Applied Science Research"},{"issue":"1","key":"76","first-page":"7","article-title":"Antimicrobial activity of leaf extracts of Senna obtusifolia (L)","volume":"2","author":"J. H. Doughari","year":"2008","journal-title":"African Journal of Pharmacy and Pharmacology"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2015.09.042"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfca.2010.09.016"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2019.05.002"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1021\/np5003252"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.1021\/np300255r"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/687859"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.10.028"},{"issue":"12","key":"84","first-page":"133","article-title":"Preliminary and pharmacological profile of Melia azedarach L.: an overview","volume":"3","author":"D. Sharma","year":"2013","journal-title":"Journal of Applied Pharmaceutical Science"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2020.01.046"},{"key":"86","article-title":"Biosynthesis of Zinc Oxide Nanoparticles Using Extracts of Moringa Oleifera: Structural & Optical Properties","author":"I. Ngom","year":"2020","journal-title":"Materials Today: Proceedings"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)97705-7"},{"key":"88","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1039\/p19870002809","article-title":"Medicinal plants of Southern Africa. Part 1. Dimeric chalcone-based pigments from Brackenridgea zanguebarica","author":"S. E. Drewes","year":"1987","journal-title":"Journal of the Chemical Society, Perkin Transactions 1"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2019.112259"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.05.019"},{"issue":"1","key":"91","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1472-6882-11-28","article-title":"Characterization of n-Hexane sub-fraction of Bridelia micrantha (Berth) and its antimycobacterium activity","volume":"11","author":"E. Green","year":"2011","journal-title":"BMC Complementary and Alternative Medicine"},{"issue":"11","key":"92","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1021\/np060418w","article-title":"Prenylated flavonoids from the root bark of Berchemia discolor, a Tanzanian medicinal plant","volume":"69","author":"Y.-W. Chin","year":"2006","journal-title":"Journal of Natural Products"},{"issue":"5","key":"93","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1179\/136485909X435111","article-title":"Crude extracts of, and purified compounds from, Pterocarpus angolensis, and the essential oil of Lippia javanica: their in-vitro cytotoxicities and activities against selected bacteria and Entamoeba histolytica","volume":"103","author":"A. Samie","year":"2013","journal-title":"Annals of Tropical Medicine and Parasitology"},{"issue":"1","key":"94","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1746-4269-9-31","article-title":"Traditional use of medicinal plants in south-central Zimbabwe: review and perspectives","volume":"9","author":"A. Maroyi","year":"2013","journal-title":"Journal of Ethnobiology and Ethnomedicine"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2011.03.022"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2015.03.046"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjp.2018.06.006"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.05.023"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2018.12.010"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.04.033"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2016.10.026"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2015.11.041"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.3923\/rjmp.2012.370.382"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2017.10.034"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.10.002"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.10.048"},{"key":"107","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.sajb.2015.01.007","article-title":"Ethnobotanical survey of medicinal plants used for traditional maternal healthcare in Katsina State, Nigeria","volume":"97","author":"S. Kankara","year":"2015","journal-title":"South African Journal of Botany"},{"issue":"1","key":"108","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13002-018-0245-4","article-title":"Ethnobotanical knowledge of the lay people of Blouberg area (Pedi tribe), Limpopo Province, South Africa","volume":"14","author":"N. I. Mongalo","year":"2018","journal-title":"Journal of Ethnobiology and Ethnomedicine"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.12.022"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.12.023"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.3109\/13880209.2011.621959"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.21010\/ajtcam.v15i1.9"},{"issue":"4","key":"113","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1055\/a-0801-8771","article-title":"A review of plants used in south African traditional medicine for the management and treatment of hypertension","volume":"85","author":"F. Balogun","year":"2019","journal-title":"Planta Medica"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1080\/10496475.2010.511075"},{"issue":"1","key":"115","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1746-4269-5-28","article-title":"An ethnobotanical study of medicinal plants in Wonago Woreda, SNNPR, Ethiopia","volume":"5","author":"F. Mesfin","year":"2009","journal-title":"Journal of Ethnobiology and Ethnomedicine"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.07.018"},{"issue":"1","key":"117","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1746-4269-6-8","article-title":"An ethnobotanical survey of medicinal plants in Babungo, Northwest Region, Cameroon","volume":"6","author":"D. J. Simbo","year":"2010","journal-title":"Journal of Ethnobiology and Ethnomedicine"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.9734\/EJMP\/2013\/1871"},{"issue":"17","key":"119","first-page":"4256","article-title":"Ethnobotanical information on plants used for the management of cardiovascular diseases in Nkonkobe Municipality, South Africa","volume":"5","author":"O. S. Olorunnisola","year":"2011","journal-title":"Journal of Medicinal Plants Research"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2015.05.029"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.01.036"},{"issue":"10","key":"122","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1021\/acs.jnatprod.6b00552","article-title":"Vobasinyl-Iboga Alkaloids from Tabernaemontana elegans: Cell Cycle Arrest and Apoptosis-Inducing Activity in HCT116 Colon Cancer Cells","volume":"79","author":"A. Paterna","year":"2016","journal-title":"Journal of Natural Products"},{"issue":"3","key":"123","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3390\/nu11030545","article-title":"Medicinal uses, phytochemistry and pharmacological properties of Elaeodendron transvaalense","volume":"11","author":"A. S. Odeyemi","year":"2019","journal-title":"Nutrients"},{"issue":"4","key":"124","article-title":"Health effects of Psidium guajava L. leaves: an overview of the last decade","volume":"18","author":"E. D\u00edaz-de-Cerio","year":"2017","journal-title":"International Journal of Molecular Sciences"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2008.01.025"},{"issue":"1","key":"126","first-page":"33","article-title":"Can guava fruit intake decrease blood pressure and blood lipids?","volume":"7","author":"R. B. Singh","year":"1993","journal-title":"Journal of Human Hypertension"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.5455\/jice.20160321115402"},{"issue":"10","key":"128","first-page":"7","article-title":"Phytochemical analysis of medicinal plants used for the management of hypertension by Esan people of Edo state, Nigeria","volume":"2009","author":"J. Mensah","year":"2009","journal-title":"Ethnobotanical Leaflets"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.1007\/s00580-015-2192-y"},{"issue":"2","key":"130","doi-asserted-by":"crossref","first-page":"10","DOI":"10.5830\/CVJA-2012-069","article-title":"Cardioprotective and anti-hypertensive effects of Prosopis glandulosa in rat models of pre-diabetes: cardiovascular topics","volume":"24","author":"B. Huisamen","year":"2013","journal-title":"Cardiovascular Journal Of Africa"},{"issue":"1","key":"131","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/1472-6882-14-147","article-title":"In vitro antibacterial, antioxidant and cytotoxic activity of acetone leaf extracts of nine under-investigated Fabaceae tree species leads to potentially useful extracts in animal health and productivity","volume":"14","author":"J. P. Dzoyem","year":"2014","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"132","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2007.569"},{"issue":"3","key":"133","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1108\/NFS-06-2018-0169","article-title":"Anti-hypertensive, anti-diabetic, hypocholesterolemic and antioxidant properties of prickly pear nopalitos in type 2 diabetic rats fed a high-fat diet","volume":"49","author":"N. el Imane Harrat","year":"2019","journal-title":"Nutrition & Food Science"},{"key":"134","volume-title":"Chemical Constituents and Biological Studies of Tagetes Minuta L. and Rauvolfia Caffra Sond","author":"S. Mlala","year":"2015"},{"issue":"4","key":"135","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0144-8617(99)00211-8","article-title":"Pharmacognosy, phytochemistry, medicinal plants (2nd ed.)","volume":"42","author":"J. Kennedy","year":"2000","journal-title":"Carbohydrate Polymers"},{"key":"136","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2013.11.005"},{"issue":"1","key":"137","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s40529-017-0196-4","article-title":"Identification of seeds based on molecular markers and secondary metabolites in Senna obtusifolia and Senna occidentalis","volume":"58","author":"R. Mao","year":"2017","journal-title":"Botanical Studies"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.4102\/ojvr.v72i3.195"}],"container-title":["Oxidative Medicine and Cellular Longevity"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2020\/6636766.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2020\/6636766.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/omcl\/2020\/6636766.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T23:32:02Z","timestamp":1697326322000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/omcl\/2020\/6636766\/"}},"subtitle":[],"editor":[{"given":"Marcio","family":"Carocho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,12,11]]},"references-count":138,"alternative-id":["6636766","6636766"],"URL":"https:\/\/doi.org\/10.1155\/2020\/6636766","relation":{},"ISSN":["1942-0994","1942-0900"],"issn-type":[{"value":"1942-0994","type":"electronic"},{"value":"1942-0900","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,11]]}}}